Fig. 1 (abstract P386).

Study protocol. At different time points several variables were collected and TCCD measurements were performed. A baseline, B increasing minute ventilation, C begin moderate hyperventilation with target PaCO2 4-4.7 kPa, D after moderate hyperventilation for 50 minutes, E return to baseline. ABG arterial blood gas. Glucose, Lactate and Pyruvate concentrations in the extracellular fluid are sampled by microdialysis one hour before A (1h-A) and one (D+1h) and two hours after D (D+2).