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Table 3 Clinical outcomes

From: Supplemental parenteral nutrition versus usual care in critically ill adults: a pilot randomized controlled study

Variable

n

Usual care

n

Intervention

p value

Patients with reported complications during study period, n (%)

 GRV > 300 ml on study days 1–7

48

23 (48)

51

28 (55)

0.49

 Abdominal distention

 

14 (29)

 

16 (31)

0.81

 Vomiting

 

8 (17)

 

13 (26)

0.28

Calories from propofol over the study period, kcal, median [IQR]

48

0 [0-110]

51

0 [0-160]

0.48

Blood test results on study day 7:

 ALP, U/L, mean (SD)

38

165 (81)

33

183 (103)

0.40

 ALT, U/L, median [IQR]

38

50 [23-86]

34

58 [30-102]

0.54

 GGT, U/L, mean (SD)

38

196 (125)

34

216 (126)

0.51

 Bilirubin, mmol/L, median [IQR]

38

15 [11-29]

35

24 [14-53]

0.47

 WCC, 0^9/L, mean (SD)

38

18 (10)

36

20 (10)

0.18

 TG, mmol/L, median [IQR]

37

2 [1-3]

32

2 [2-4]

0.18

 CRP, mg/L, median [IQR]

37

110 [78-185]

32

153 [105-216]

0.06

Mean SOFA over study duration, mean (SE)

48

8.0 (0.4)

51

8.2 (0.4)

0.75

Duration of mechanical ventilation, days, median [IQR]

48

8 [5-18]

51

10 [6-15]

0.68

Duration of ICU stay, days, median [IQR]

48

11 [6-17]

51

11 [5-17]

0.83

Duration of hospital stay, days, mean (SD)

48

23 (17)

51

22 (21)

0.85

Survival

 ICU D/C, n (%)

 

37 (77)

 

36 (71)

0.46

 Hospital D/C, n (%)

48

37 (77)

51

35 (67)

0.37

 90 days, n (%)

 

35 (73)

 

32 (63)

0.28

 180 days, n (%)

 

35 (73)

 

32 (63)

0.28

EQ-5D-3L

 Hospital D/C, mean (SD)

17

0.32 (0.36)

27

0.25 (0.34)

0.54

 90 days, median [IQR]

29

0.76 (0.23)

35

0.69 (0.24)

0.29

 180 days, mean (SD)

29

0.77 (0.24)

35

0.75 (0.26)

0.76

Hand grip strength at hospital D/C, kg, mean (SD)

24

20 (8)

19

19 (13.5)

0.71

ICU mobility scale at hospital D/C, median [IQR]

33

8 [4-10]

25

9 [5-10]

0.58

Mid arm muscle circumference, hospital D/C, cm, mean (SD)

25

30 (5)

22

30 (5)

0.91

  1. The highest level of function scale ranges from 0 to 10 with 0 being ‘no mobility’ (lying in bed) and 10 being ‘Walking independently without a gait aid’ [23].
  2. ALT alanine aminotransferase, ALP alkaline phosphatase, BMI body mass index, CRP C-reactive protein, D/C discharge, ED Emergency department, EQ-5D-3L EuroQuol-5 Dimension 3 Level, GGT gamma glutamyltransferase, GRV gastric residual volume, ICU intensive care unit, IQR interquartile range, SD Standard deviation, SOFA Sequential Organ Failure Assessment, TG triglyceride, WCC white cell count