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Table 2 Healthcare costs split by major cost categories

From: Cost-effectiveness study of early versus late parenteral nutrition in critically ill children (PEPaNIC): preplanned secondary analysis of a multicentre randomised controlled trial

Cost category

Early PN, €

Late PN, €

Mean difference

(95% CI), €

P value

(t test)

Mean

SD

p25–p75

Mean

SD

p25–p75

  

ICU hospitalisation

13.710

35.130

2.270–13.250

9.590

16.730

2.270–9.070

-4.120 (-7.590; -1.500)

0.003

Medication

1.810

7.430

250–1000

1.160

3.080

220–830

-650 (-1.360; 100)

0.03

Ventilator support

1.740

6.650

150–1.430

1.100

2.300

150–1.070

-640 (-1.260; -190)

0.03

Post-ICU hospitalisation

7.140

14.530

1.500–6.900

6.560

14.270

1.500–6.270

-580 (-2.100; 1.080)

0.24

Surgery

4.760

5.480

280–6.500

4.240

4.260

200–6.280

-520 (-1.080; 10)

0.03

Laboratory diagnostics

2.290

4.090

540–2.160

1.820

3.370

440–1.820

-460 (-860; -40)

0.01

PN

300

500

60–300

150

270

20–170

-150 (-200; -110)

<0.001

Other diagnostics

690

2.020

80–550

610

1.610

80–430

-80 (-290; -110)

0.20

Consultations

470

690

40–680

440

630

30–680

-30 (-100; 50)

0.19

RRT and mechanical hemodynamic support

950

6.740

0–0

1.010

9.370

0–0

60 (-810; 1.020)

0.45

Total

33.860

57.610

11.080–34.720

26.680

35.850

10.090–28.830

-7.180 (-12.920; -1.880)

0.007

  1. Cost categories were ranked according to the mean difference between the treatment groups
  2. PN parenteral nutrition, CI confidence interval, ICU Intensive Care Unit, RRT renal replacement therapy, p25–p75 25th to 75th percentile