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Table 1 Patient characteristics

From: Determinants of long-term outcome in ICU survivors: results from the FROG-ICU study

Variable % of missing value Studied patients 1 year post ICU p value
(n = 1570) Survivors (n = 1237) Nonsurvivors (n = 333)
Age (years) 0.0 61 (49; 73) 58 (47; 70) 71 (61; 79) < 0.01
Male gender 0.0 1000 (63.7) 782 (63%) 218 (66%) 0.48
BMI (kg/m2) 37.5 26 (23; 31) 26 (23; 31) 26 (23; 31) 0.96
Charlson score 0.1 3 (1; 4) 2 (1; 4) 4 (3; 6) < 0.01
Deprivation index (FDep) 10.8 −0.6 (−1.6; 0.3) −0.6 (−1.6; 0.3) −0.6 (−1.5; 0.4) 0.44
SOFA score at admission 37.2 6 (4; 9) 7 (4; 10) 8 (5; 11) 0.11
SAPS II score at admission 0.1 46 (34; 59) 45 (33; 58) 51 (40; 65) < 0.01
Main cause of admission      < 0.01
 Septic shock 0.1 339 (22%) 244 (20%) 95 (29%)  
 Acute respiratory failure   303 (19%) 230 (19%) 73 (22%)
 Acute neurological disorder   241 (15%) 210 (17%) 31 (9%)
 Out-of-hospital cardiac arrest   117 (8%) 102 (8%) 15 (5%)
In-ICU management
 In-ICU LOS (days) 0.0 12 (7; 21) 12 (7; 20) 13 (7; 24) 0.03
 In-hospital LOS (days) 0.1 26 (15; 43) 25 (15; 43) 28 (16; 47) 0.05
 Tracheotomy 0.0 241 (15%) 181 (15%) 60 (18%) 0.13
 RRT 0.0 286 (18%) 202 (16%) 84 (25%) < 0.01
 Inotrope/vasopressor 0.0 1151 (73%) 888 (72%) 263 (79%) < 0.01
 RBC 0.0 676 (43%) 490 (40%) 186 (56%) < 0.01
 FFP 0.0 236 (15%) 171 (14%) 65 (20%) < 0.01
Status at discharge
 SBP (mmHg) 12.9 125 (111; 139) 125 (112; 139) 122 (108; 139) 0.03
 DBP (mmHg) 16.7 68 (59; 76) 69 (60; 77) 64 (55; 73) < 0.01
 HR (bpm) 14.1 90 (79; 101) 90 (79; 100) 89 (79; 101) 0.41
 Atrial fibrillation 10.0 297 (21%) 265 (21%) 32 (21.2) 0.96
 Temperature (°C) 10.3 37.1 (36.8; 37.5) 37.1 (36.8; 37.5) 37 (36.6; 37.4) < 0.01
 Sodium (mmol/l) 3.1 139 (136; 142) 139 (136; 142) 139 (136; 142) 0.6
 Potassium (mmol/l) 8.3 3.9 (3.6; 4.2) 3.9 (3.6; 4.2) 4.0 (3.6; 4.2) 0.36
 Creatinine (μmol/l) 3.7 66 (51; 95) 64 (50; 87) 80 (57; 131) < 0.01
 eGFR (ml/min/1.73 m2) 3.7 91 (51.2; 110) 110 (75; 146) 79 (46; 119) < 0.01
 Lactate (mmol/l) 58.3 1.0 (0.7; 1.3) 1.0 (0.7; 1.3) 1.1 (0.8; 1.4) < 0.01
 WBC count (/mm3) 13.6 9600 (7015; 13,100) 9500 (7000; 12,952) 10050 (7342; 13,962) 0.04
 Hemoglobin (g/dl) 13.6 10.0 (9.0; 11.2) 10.2 (9.1; 11.3) 9.6 (8.7; 10.6) < 0.01
 Platelets count (/mm3) 12.9 291,500 (181,750; 432,500) 308,500 (191,000; 457,000) 240500 (137,500; 347,750) < 0.01
 Bilirubin (mmol/l) 63.2 11 (7; 20) 10 (7; 19) 14 (9; 36) < 0.01
 Glycemia (mmol/l) 16.8 6.8 (5.7; 8.3) 6.7 (5.7; 8.2) 7.1 (5.9; 8.7) 0.01
 Total protein (g/L) 18.6 62 (56; 69) 63 (57; 69) 60 (52; 66) < 0.01
  1. Results expressed as count (percentage) or median (interquartile range)
  2. BMI body mass index, SOFA Sequential Organ Failure Assessment, SAPS Simplified Acute Physiology Score, ICU intensive care unit, LOS length of stay, RRT renal replacement therapy, RBC red blood cell transfusion, FFP fresh frozen plasma transfusion, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, eGFR estimated glomerular filtration rate, WBC white blood cell