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Table 1 Individual outlying epochs with relative search volume above the modeled baseline

From: Global trends in the awareness of sepsis: insights from search engine data between 2012 and 2017

Week

RSV

Effect duration in weeks (impact per week)

Potential awareness and media correlates

p value (per week)

Individual positive outlying epochs

 8 July 2012

52

1 (+3.25)

Pediatric sepsis death in the USA

< 0.0001

 11 November 2012

59

1 (+15.95)

Adult death following septic miscarriage in Ireland

< 0.0001

 30 November 2014

62

1 (+14.05)

Adult deaths from sepsis secondary to contaminated sharps in India

< 0.0001

 11 January 2015

57

1 (+8.26)

Adult sepsis death in the USA

0.0002

 24 January 2016

80

1 (+26.0)

NHS report on, and wide coverage of, a pediatric sepsis death in the UK

< 0.0001

 27 March 2016

93

3 (+36.86, +6.04, +5.53)

Death of Patty Duke from abdominal sepsis in the USA

< 0.0001, 0.0068, 0.0135

 29 May 2016

69

2 (+13.83, +44.66)

Death of Muhammad Ali

< 0.0001, < 0.0001

 11 September 2016

84

3 (+18.36, +10.16, +8.33)

Inaugural World Sepsis Congress, fifth World Sepsis Day with international coverage, US CDC awareness efforts

< 0.0001, < 0.0001, 0.0004

 2 October 2016

72

1 (+10.95)

Adult sepsis death in the UK

< 0.0001

 1 January 2017

68

1 (+7.0)

Pediatric sepsis death in the USA

0.0012

 19 February 2017

70

1 (+6.24)

Multiple news media correlates

0.0049

 5 March 2017

73

1 (+8.18)

NHS sepsis 1-hour intervention mandate in the UK

0.0003

 19 March 2017

72

1 (+6.41)

Coverage of vitamin C as a potential therapeutic intervention

0.0042

 26 March 2017

81

1 (+16.03)

Additional vitamin C coverage, NHS apology regarding pediatric sepsis death

< 0.0001

Starting year

Week

Impact coefficient

Potential correlates

 

Cyclic outlying effects

  

 2012

37

+7.82

World Sepsis Day

< 0.0001

 2012

51

–2.82

Holiday season

0.0042

 2012

52

–7.60

< 0.0001

  1. CDC Centers for Disease Control, NHS National Health Service, RSV relative search volume