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Table 1 Patient characteristics at admission

From: Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients

 

V

V/IC

V/PT

p value

Adults

n = 112

n = 53

n = 81

 

 Age (years)

46 ± 16

44 ± 16

41 ± 17

0.10

 Sex (male:female), n

70:39

41:12

78:23

0.09

 TBSA (%)

13.5 ± 15

12 ± 12

15 ± 17

0.46

 Inhalation injury, n (%)

11 (10)

6 (11)

10 (10)

0.90

 Cause of burn, n (%)

   

ns

  Flame

94 (84)

68 (90)

87 (88)

 

  Scald

7 (6)

2 (2)

6 (6)

  Electrical

6 (5)

5 (6)

2 (2)

  Other

5 (5)

1 (2)

4 (4)

 CRBL (mg/dl)

0.80 ± 0.18

0.79 ± 0.19

0.81 ± 0.19

0.96

Children

n = 26

n = 268

n = 178

 

 Age (years)

8 ± 6

7 ± 5

7 ± 6

0.62

 Sex (male:female), n

17:9

165:103

114:64

0.83

 TBSA (%)

32.0 ± 18

39 ± 19

40 ± 18

0.10

 Inhalation injury, n (%)

3 (12)

48 (18)

19 (11)

0.10

 Cause of burn, n (%)

   

ns

  Flame

13 (50)

137 (51)

105 (59)

 

  Scald

7 (26)

102 (38)

57 (32)

  Electrical

2 (8)

24 (9)

11 (6)

  Other

4 (15)

5 (2)

5 (2)

 CRBL (mg/dl)

0.46 ± 0.28

0.50 ± 0.22

0.50 ± 0.21

0.70

  1. Values are shown as mean ± SD unless otherwise indicated
  2. CR BL baseline creatinine concentration, IC imipenem-cilastin, ns not significant, PT piperacillin-tazobactam, TBSA total body surface area burned, V vancomycin