From: Chloral hydrate enteral infusion for sedation in ventilated children: the CHOSEN pilot study
Variable | CHOSEN (n = 21) | Controls (n = 21) | p value |
---|---|---|---|
Age (months) | 11.4 (12.1) | 14.0 (19.6) | 0.61 |
7 (IQR 3, 18) | 9 (IQR 5, 13) | ||
Age category (<1; 1–5; 6–12 years) | 13; 8; 0 | 16; 4; 1 | 0.27 |
Weight (kg) | 8.6 (3.6) | 8.3 (5.5) | 0.87 |
8.9 (IQR 5.5, 11.2) | 7 (IQR 4.6, 9.8) | ||
Gender male | 15 (71%) | 11 (52%) | 0.34 |
Cardiac surgical | 0 | 5 (24%)a | 0.048 |
General surgical | 4 (19%) | 5 (24%) | 0.99 |
Medical | 18 (86%) | 13 (62%) | 0.16 |
Bronchiolitis | 10 (48%) | 4 (19%) | 0.10 |
Inotrope used | 2 (10%) | 2 (10%) | 0.99 |
Epinephrine or norepinephrine used | 2 (10%) | 2 (10%) | 0.99 |
Inotrope score | 0.5 (1.5) | 1.1 (4.4) | 0.52 |
Absolute inotrope scores | 5, 5 | 4, 20 | |
Lactate measured | 19 | 21 | 0.49 |
Lactate (mmol/L) | 0.7 (0.2) | 1.0 (0.6) | 0.02 |
Creatinine measured | 15 | 17 | 0.72 |
Creatinine (umol/L) | 21 (5) | 21 (10) | 0.81 |
PRISM | 2.5 (2.3) | 3.0 (2.5) | 0.48 |
3 (0, 5) | 3 (1, 5) | ||
PELOD | 6.2 (5.2) | 6.5 (5.0) | 0.88 |
2 (1, 11) | 10 (1, 11) | ||
Invasive ventilation | 21 (100%) | 18 (86%)b | 0.23 |