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Table 1 Baseline variables for cases and controls

From: Chloral hydrate enteral infusion for sedation in ventilated children: the CHOSEN pilot study

Variable

CHOSEN (n = 21)

Controls (n = 21)

p value

Age (months)

11.4 (12.1)

14.0 (19.6)

0.61

7 (IQR 3, 18)

9 (IQR 5, 13)

Age category (<1; 1–5; 6–12 years)

13; 8; 0

16; 4; 1

0.27

Weight (kg)

8.6 (3.6)

8.3 (5.5)

0.87

8.9 (IQR 5.5, 11.2)

7 (IQR 4.6, 9.8)

Gender male

15 (71%)

11 (52%)

0.34

Cardiac surgical

0

5 (24%)a

0.048

General surgical

4 (19%)

5 (24%)

0.99

Medical

18 (86%)

13 (62%)

0.16

Bronchiolitis

10 (48%)

4 (19%)

0.10

Inotrope used

2 (10%)

2 (10%)

0.99

Epinephrine or norepinephrine used

2 (10%)

2 (10%)

0.99

Inotrope score

0.5 (1.5)

1.1 (4.4)

0.52

Absolute inotrope scores

5, 5

4, 20

Lactate measured

19

21

0.49

Lactate (mmol/L)

0.7 (0.2)

1.0 (0.6)

0.02

Creatinine measured

15

17

0.72

Creatinine (umol/L)

21 (5)

21 (10)

0.81

PRISM

2.5 (2.3)

3.0 (2.5)

0.48

3 (0, 5)

3 (1, 5)

PELOD

6.2 (5.2)

6.5 (5.0)

0.88

2 (1, 11)

10 (1, 11)

Invasive ventilation

21 (100%)

18 (86%)b

0.23

  1. Data given as n (%), or mean (SD), or median (IQR). Comparisons by Fisher’s exact test and t test, as appropriate. PELOD pediatric logistic organ dysfunction score, PRISM pediatric risk of mortality score
  2. acongenital heart disease were: atrial septal defect (n = 1); tetralogy of Fallot (n = 2); other (n = 1)
  3. bThree control patients had only non-invasive ventilation used