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Table 4 Adjusted odds ratios for hospital death

From: Kinetic estimated glomerular filtration rate in critically ill patients: beyond the acute kidney injury severity classification system

 

Odds ratio (95% confidence interval)

KeGFR (ml/min/1.73 m2)

No AKI (n = 3922)

AKI stage 1 (n = 3996)

AKI stage 2 (n = 3826)

AKI stage 3 (n = 1540)

>70

Reference

Reference

Reference

Reference

45–70

1.39 (1.00–1.94)

2.41 (1.91–3.19)

0.86 (0.66–1.32)

1.79 (1.09–2.54)

30–45

1.45 (0.64–2.986)

2.47 (1.44–4.35)

1.62 (1.28–1.71)

2.28 (1.38–2.63)

<30

3.71 (2.14–5.90)

5.43 (3.48–7.99)

1.73 (1.34–2.31)

4.39 (2.59–5.29)

  1. Observe that the worst KeGFR is associated with hospital death even after dividing patients by maximum AKI stage
  2. Adjusted for age, gender, SAPS II score, SOFA score, main comorbidities (hypertension, congestive heart failure, cardiac arrhythmias, chronic pulmonary obstructive disease, diabetes mellitus, lymphoma, metastatic cancer, liver disease, obesity), type of admission (clinical or surgical), baseline estimated glomerular filtration rate, need for vasoactive drugs, and mechanical ventilation
  3. AKI acute kidney injury, KeGFR kinetic estimated glomerular filtration rate