| CIN (n = 21) | No CIN (n = 103) | P value |
---|---|---|---|
Age (years) | 54 (4.90) | 50.80 (2.12) | 0.55 |
Male gender, n (%) | 17 (80.95) | 79 (76.69) | 0.78 |
Weight (Kg) | 73.23 (2.32) | 68.15 (1.34) | 0.68 |
Height (cm) | 164 | 169 | 0.57 |
BMI (Kg/m2) | 27 | 26 | 0.80 |
APACHE II score | 14.95 (1.79) | 13.68 (0.69) | 0.51 |
SOFA score | 6.53 (0.8) | 5.69 (0.34) | 0.34 |
Category of admission | |||
 Medical, n (%) | 9 (42.86) | 44 (42.72) | 0.15 |
 Surgical, n (%) | 2 (9.52) | 27 (26.21) | 0.15 |
 Neurosurgical, n (%) | 10 (47.62) | 32 (31.07) | 0.20 |
Comorbidities | |||
 Diabetes, n (%) | 2 (9.52) | 10 (9.71) | 0.68 |
 Hypertension, n (%) | 4 (19.05) | 32 (31.07) | 0.57 |
 Cardiovascular, n (%) | 3 (14.29) | 11 (10.68) | 0.70 |
 Cirrhosis, n (%) | 1 (4.76) | 0 | 0.16 |
 Renal disease, n (%) | 1 (4.76) | 6 (5.83) | 0.41 |
 Sepsis, n (%) | 8 (38.10) | 35 (33.98) | 0.80 |
 COPD, n (%) | 3 (14.28) | 16(15.53) | 1.00 |
 Charlson index score | 2.32 (0.57) | 2.10 (0.24) | 0.70 |
Serum creatinine (mg/dl) | 0.87 (0.08) | 0.96 (0,07) | 0.39 |
Serum cystatin-C (mg/L) | 1.34 (0.23) | 0.98 (0.05) | 0.14 |
Serum urea (mg/dl, median) | 55 (8.34) | 44 (3.82) | 0.18 |
Serum urea/creatinine | 73.19 (6.3) | 58.65 (2.5) | 0.01 |
Fluid balance/24Â h (ml) | 1462 (169) | 1058 (338.1) | 0.30 |
Vasoactive therapy, n (%) | 9 (42.86) | 45 (43.69) | 0.13 |
Noradrenaline dose, γ | 0.1 (0.05) | 0.06 (0.01) | 0.20 |
Mechanical ventilation, n (%) | 15 (71.43) | 51 (49.51) | 0.09 |
Diuretic therapy, n (%) | 1 (4.76) | 19 (18.45) | 0.19 |
ACEi or ARBs, n (%) | 7 (33.33) | 20 (19.42) | 0.19 |
Nephrotoxic medications, n (%) | 19 (90.48) | 68 (66.02) | 0.03 |
Volume of contrast agent (ml) | 126.3 (5.88) | 122.2 (2.77) | 0.53 |
Multiple studies, n (%) | 6 (28.57) | 13 (12.62) | 0.09 |
Length of ICU stay (days, median) | 29 (3.97) | 25 (7.85) | 0.80 |
Length of ICU stay before entering the study (days) | 20.71 (4.4) | 18.15 (2.7) | 0.68 |
ICU mortality, n (%) | 6 (28.57) | 20 (19.42) | 0.38 |
RRT 10Â days post contrast agent, n (%) | 3 (14.28) | 4 (4.85) | 0.09 |
Total duration on RRT (h) | 47.67 (17.32) | 49.25 (9.29) | 0.93 |