Fig. 2From: Metabolome alterations in severe critical illness and vitamin D statusPartial least squares-discriminant analysis (PLS-DA). Cross-validated PLS-DA score plot for comparison of the global metabolite profiles of 24 patients with 25(OH)D ≤ 5 ng/ml (red) and 41 patients with 25(OH)D >15 ng/ml (green) shows the separation achieved according to vitamin D status. The p value based on permutation is 0.033 (66/2000). Colored circles represent 95% confidence intervals. Colored dots represent individual samples: 4.5% and 5.3% are the scores of component 1 and component 2, respectively, in the PLS-DA analysisBack to article page