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Table 3 Clinical characteristics of patients with acute pancreatitis with or without infectious complications

From: Monocyte programmed death ligand-1 expression is an early marker for predicting infectious complications in acute pancreatitis

 

Non-IC group (n = 38)

IC group (n = 25)

p Value

Age, years

45.34 ± 2.56

53.60 ± 2.53

0.037

Female/male, n

14/24

8/17

 

WBC count, ×109/L

12.49 ± 0.93

13.32 ± 1.06

0.559

BUN, mmol/L

12.71 ± 1.26

17.22 ± 2.49

0.088

Hematocrit

0.41 ± 0.01

0.42 ± 0.02

0.701

APACHE II score

10 ± 0.68

15.12 ± 1.10

0.000

Lymphocyte count on day 1, ×109/L

1.00 ± 0.05

0.79 ± 0.05

0.012

Lymphocyte count on day 3, ×109/L

1.08 ± 0.06

0.86 ± 0.06

0.016

IL-10 concentration on day 1, pg/ml

30.83 ± 1.56

41.86 ± 2.56

0.000

IL-10 concentration on day 3, pg/ml

26.09 ± 1.37

32.85 ± 2.24

0.017

Percentage of HLA-DR expression on CD14+ monocytes on day 1

44.51 ± 2.19

36.30 ± 2.99

0.027

Percentage of HLA-DR expression on CD14+ monocytes on day 3

46.64 ± 2.01

37.24 ± 2.86

0.010

Percentage of PD-1 expression on CD4+ lymphocytes on day 1, (%)

33.31 ± 1.40

38.83 ± 2.02

0.024

Percentage of PD-1 expression on CD4+ lymphocytes on day 3

28.98 ± 1.13

33.38 ± 1.95

0.041

Percentage of PD-L1 expression on CD14+ monocytes on day 1

22.96 ± 1.42

29.94 ± 2.26

0.010

Percentage of PD-L1 expression on CD14+ monocytes on day 3

30.00 ± 1.04

34.46 ± 1.67

0.020

Mortality

2 (9.09%)

2 (6.67%)

1.000

  1. Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, BUN Blood urea nitrogen, IL Interleukin, HLA-DR Human leukocyte antigen-DR, IC Infectious complications, PD-1 Programmed cell death receptor 1, PD-L1 Programmed cell death receptor ligand 1, WBC White blood cell
  2. Data are shown as mean ± SEM