Table 5 Comparison between cirrhotic and noncirrhotic groups matched according to age and sex

Age (years)

56.0 ± 14.9

58.1 ± 20.5

0.556

Gender (M/F)

36/10

36/10

1.000

SOFA score

12.7 ± 4.1

6.7 ± 4.1

<0.001

Baseline cortisol (nmol/L)

748 (450–1203)

778 (590–1109)

0.628

Peak cortisol (nmol/L)

993 (744–1479)

1195 (948–1589)

0.041

Cortisol increment (nmol/L)

221 (121–348)

408 (285–570)

<0.001

ACTH (pg/ml)

19.1 (9.1–34.0)

20.3 (8–30.5)

0.842

Baseline DHEAS (nmol/L)

703 (464–1180)

842 (587–1432)

<0.001

Peak DHEAS (nmol/L)

939 (497–1296)

1037 (643–1752)

<0.001

DHEAS increment (nmol/L)

89.6 (23–185)

325.7 (174–546)

<0.001

Baseline DHEAS/cortisol

1.40 ± 1.24

3.86 ± 2.57

0.001

IL-6 (pg/ml)

424 (206–855)

88 (35–275)

0.002

TNF-α (pg/ml)

34 (21–70)

15 (10.65–23.5)

0.003

Hospital mortality

34/46 (73.9%)

16/46 (34.8%)

<0.001