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Table 3 Sensitivity, specificity, PPV, NPV, LR+, and LR– of BDG and PCT used in combination for the diagnosis of candidaemia over bacteraemia in the study population

From: Combined use of serum (1,3)-β-d-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units

 

No./total patients

      

Cut-off

Candidaemia (TP/total)

Bacteraemia (TN/total)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

LR+

LR–

BDG ≥80 pg/ml and/or PCT <2 ng/ml

70/73

56/93

96

60

65

95

2.41

0.07

BDG ≥80 pg/ml and PCT <2 ng/ml

48/73

91/93

66

98

96

78

30.58

0.35

  1. BDG (1,3)-β-d-glucan, LR+ positive likelihood ratio, LR– negative likelihood ratio, NPV negative predictive value, PCT procalcitonin, PPV positive predictive value, TN true negatives, TP true positives
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Critical Care

ISSN: 1364-8535