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Table 3 Sensitivity, specificity, PPV, NPV, LR+, and LR– of BDG and PCT used in combination for the diagnosis of candidaemia over bacteraemia in the study population

From: Combined use of serum (1,3)-β-d-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units

  No./total patients       
Cut-off Candidaemia (TP/total) Bacteraemia (TN/total) Sensitivity (%) Specificity (%) PPV (%) NPV (%) LR+ LR–
BDG ≥80 pg/ml and/or PCT <2 ng/ml 70/73 56/93 96 60 65 95 2.41 0.07
BDG ≥80 pg/ml and PCT <2 ng/ml 48/73 91/93 66 98 96 78 30.58 0.35
  1. BDG (1,3)-β-d-glucan, LR+ positive likelihood ratio, LR– negative likelihood ratio, NPV negative predictive value, PCT procalcitonin, PPV positive predictive value, TN true negatives, TP true positives