Fig. 2
From: The future of mechanical ventilation: lessons from the present and the past
Lung strain (tidal volume/FRC) as a function of lung stress (transpulmonary pressure). Data adapted from Agostoni and Hyatt [74]. As shown, the doubling of the FRC occurs at a transpulmonary pressure of 12 cmH2O (specific elastance). We arbitrarily indicated the ‘risky’ zone of P L as that which corresponds to lung strains exceeding 1.5 (based on experimental data [52]). P L transpulmonary pressure