Fig. 3

Modulation of gene expression induced by hydrocortisone administration after burn shock. a Heatmap representation of expression in genes specifically modulated by hydrocortisone. Gene expression (rows) is color-coded from blue to orange. Individual values were averaged according to sampling time (columns), and the associated number of patients is presented above each column. Four (1 to 4) clusters were identified by unsupervised analysis, according to a similar longitudinal profile of expression, and illustrated as boxplots (b-e). Hydrocortisone-treated patients are in purple while placebo-treated patients are in green. S1 to S4 sample times day 0, day 1, day 5 and day 7, respectively, HV healthy volunteers