Table 1 Summary of studies using RIFLE, AKIN, and KDIGO criteria for outcome evaluation

Zarbock 2016 [24]

Predominantly surgical

CVVH

KDIGO stage 2 AKI

eGFR < 30 ml/min/1.73 m², previous RRT, AKI caused by permanent occlusion of renal artery or surgery, GN, IN, HUS, AIDS, HRS, pregnancy

231

30-day, 60-day and 90-day mortality

Gaudry 2016 [23]

Mixed

Mixed

Ischemic or toxic AKI and receiving MV, catecholamine infusion or both, and KDIGO stage 3 AKI

BUN > 112 mg/dl, sK > 6.0 mmol/L, pH < 7.15, acute pulmonary edema

619

30-day and 60-day mortality

Sabater 2009 [14]

Medical

CVVH

N/A

N/A

148

In-hospital mortality

Shiao 2009 [15]

Surgical

CRRT/SLED/IHD

Postoperative AKI requiring RRT in ICU (s/p major abdominal surgery)

Age < 18 years; ICU stay < 2 days; RRT started before surgery; no abdominal surgery; renal transplant

98

In-hospital mortality

Chou 2011 [16]

Medical

CRRT/ SLED

Septic AKI s/p acute RRT

Age <18 years; ICU stay < 2 days; RRT < 2 days

370

In-hospital mortality

Wu 2012 [17]

Surgical

CRRT

(1) AKI with sK > 6.0 meq/L, (2) metabolic acidosis (sHCO₃ < 12 meq/L), (3) pulmonary edema refractory to diuretics, or (4) oliguria with progressive azotemia, especially in hemodynamically unstable patients

N/A

73

60-day and 90-day mortality

Boussekey 2012 [18]

Mixed

N/A

ICU patients in need of RRT

N/A

110

In-hospital mortality

Hu 2013 [19]

Mixed

CRRT

AKI with CRRT

CKD

52

In-hospital mortality

Shum 2013 [20]

Medical

CRRT

Septic AKI

Cardiothoracic surgery, transplant surgery, and burns

120

In-hospital mortality

Leite 2013 [21]

Mixed

SLED

ICU patients on acute RRT

CKD

150

In-hospital mortality

Suzuki 2013 [22]

Mixed

CRRT

AKI with CRRT

N/A

189

In-hospital mortality