Fig. 3From: Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsisIsolated brain mitochondrial respiration in cohort 1 animals. Red horizontal bars represent median values. Black filled circles represent animals that died during the resuscitation period. p Values provided were calculated with an independent-samples t test or the Mann-Whitney U test. State 3 represents active respiration after addition of adenosine diphosphate (ADP), and state 4 represents the respiration after depletion of ADP. The respiratory control ratio (RCR) was calculated by dividing state 3 by state 4 respiration rates. a Complex I. b Complex II. c Complex â IVBack to article page