Pre-admission functional status impacts the performance of the APACHE IV model of mortality prediction in critically ill patients

Table 2 Observed-expected mortality ratios, stratified by FS and APIV PM

Cohort	Number	Mortality (%)	APIV PM (%)	OE MR
APIV PM <10%
FS1	5054	1.1	3.3	0.33
FS2	434	5.1	5.6	0.91
FS3	41	4.9	4.9	1.00
APIV PM <10–25%
FS1	1279	7.9	16.1	0.49
FS2	490	16.1	16.8	0.96
FS3	49	20.4	17.0	1.20
APIV PM <25–50%
FS1	671	21.3	35.1	0.61
FS2	411	32.1	36.3	0.89
FS3	62	29.0	37.2	0.78
APIV PM ≥50%
FS1	710	65.2	75.4	0.86
FS2	393	71.5	75.8	0.94
FS3	44	63.6	70.1	0.91

APIV PM Acute Physiology and Chronic Health Evaluation IV (APACHE IV) predicted mortality (%), OE MR observed-expected mortality ratio. Statistical testing for differences between FS for OE MR:APIV PM <10%; FS1 vs FS2 p < 0.0001; FS1 vs FS3 p < 0.0001. APIV PM <10–25%; FS1 vs FS2 p < 0.0001; FS1 vs FS3 p < 0.0001. APIV PM <25–50%; FS1 vs FS2 p < 0.0001; FS1 vs FS3 p = 0.0082. APIV PM ≥50%; FS1 vs FS2 p = 0.0001; FS1 vs FS3 p = 0.3494

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