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Table 2 Retinal fluorescein angiography: retinal changes, ocular pressure, tissue perfusion parameters, and inflammatory markers

From: Retinal arterial blood flow and retinal changes in patients with sepsis: preliminary study using fluorescein angiography

 

All patients (N = 31)

Patients with short arterial filling time <8.28 seconds (n = 15)

Patients with prolonged arterial filling time >8.28 seconds (n = 16)

P value

Intraocular pressure at angiography, mmHg

15.7 [13.3–19.5]

14.0 [12.5–15.5]

17.8 [14.7–22.1]

0.031

Retinal changes, n (%)

16 (51.6)

3 (20)

13 (81.3)

0.001

Mean blood glucose level, mmol/L

7.8 [6.8–10.4]

8.9 [7.7–10.2]

8.1 [7.2–9.4]

0.36

CRP at angiography, mg/L

160 [114–316]

254 [146–366]

139 [77.7–224.5]

0.011

CRP, highest before angiography, mg/L

264 [149–380]

307 [161.7–435.7]

187 [99.5–363.5]

0.104

PCT at angiography, μg/L

3.87 [1.96–12.2]

0.387 [1.96–12.2]

7.06 [1.9–31.8]

0.28

PCT, maximum before angiography, μg/L

9.4 [2.4–36.6]

11.6 [6.7–30.3]

6.7 [0.96–61.9]

0.669

Platelets, lowest before angiography, ×109/L

170 [124–219]

184.5 [166–270.7]

146 [98.5–202.3]

0.056

Platelets, lowest at angiography, ×109/L

149 [90–185]

167 [123–209]

96 [84–178]

0.07

PT-INR, highest before angiography

1.3 [1.15–1.9]

1.2 [1.1–1.6]

1.45 [1.27–2.2]

0.025

PT-INR, highest at angiography

1.35 [1.2–1.67]

1.25 [1.17–1.45]

1.45 [1.2–2.1]

0.09

Noradrenaline dose, highest before angiography, μg/kg/minute

0.2 [0.06–0.53]

0.23 [0.073–0.64]

0.167 [0–0.38]

0.47

Noradrenaline dose during angiography, μg/kg/minute

0.04 [0–0.24]

0.0242 [0–0.61]

0.050 [0.005–0.23]

0.71

Cardiac index, lowest before angiography, L/minute/m2

2.4 [1.7–3]

3.1 [2.5–3.2]

2.1 [1.7–2.5]

0.042

Cardiac index, during angiography, L/minute/m2

2.3 [1.9–2.7]

2.6 [2.2–3.1]

2.1 [1.7–2.4]

0.039

MAP at angiography, mmHg

73.9 [68–88]

78.5 [69.5–88.8]

69.6 [65.5–89.2]

0.49

MAP below 65 mmHg before angiography, minutes

13.6 [8–33]

11 [4.5–37.5]

23 [8–33]

0.470

Lactate angiography, mmol/L

1.9 [1.3–2.5]

1.75 [1.31–2.5]

1.98 [1.34–2.54]

0.62

Lactate, highest before angiography, mmol/L

3.4 [1.9–8.6]

2.97 [2.2–6.7]

6.05 [1.87–10.03]

0.61

BE lowest before angiography, mmol/L

−7.8 [−13.5 to −4.8]

−7.8 [−12.9 to −3.3]

−7.9 [−14.1 to −7]

0.467

BE during angiography, mmol/L

−4.3 [−7.9 to 0.375]

−3.2 [−7.5 to 0]

−4.9 [−11.1 to 0.9]

0.57

PaO2, mmHg

12.3 [11.4–14.5]

11.4 [10.3–13.8]

12.2 [9.9–13]

0.66

PaCO2, mmHg

4.9 [4.5–6]

5.2 [4.6–6]

5.1 [4.2–5.9]

0.77

PaO2/FiO2 ratio, mmHg

31.5 [23.6–37.1]

34.6 [23.8–47.9]

34.2 [23.8–43.7]

0.95

  1. Abbreviations: CRP, C-reactive protein, PCT, Procalcitonin, PT-INR, Prothrombin time international normalized ratio, MAP, Mean arterial pressure, BE, Base excess, PaCO 2 , Partial pressure of carbon dioxide in arterial blood, PaO 2 /FiO 2 ratio Ratio of partial pressure of oxygen in arterial blood to fraction of inspired oxygen