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Table 1 Patient characteristics and outcomes

From: Cardiac biomarkers are associated with maximum stage of acute kidney injury in critically ill patients: a prospective analysis

Parameter

All (n = 138)

No AKI (n = 65)

Any AKI (n = 73)

p value

Baseline characteristics

 Age, median (IQR)

65.5 (49–76)

61 (41–72)

69 (54–77)

0.006

 Male gender, n (%)

80 (58.0)

41 (63.1)

39 (53.4)

0.252

Comorbidities

 IHD, n (%)

22 (15.9)

11 (16.9)

11 (15.1)

0.766

 Hypertension, n (%)

49 (35.5)

21 (32.3)

28 (38.4)

0.459

Admission diagnosis category, n (%)

 Acute kidney injury

8 (5.8)

–

8 (11.0)

 

 Cardiac emergency

6 (4.3)

3 (4.6)

3 (4.1)

 

 Gastrointestinal emergency

13 (9.4)

8 (12.3)

5 (6.8)

 

 Liver failure

3 (2.1)

–

3 (4.1)

 

 Metabolic emergency

4 (2.9)

–

4 (5.5)

 

 Neurological emergency/overdose

13 (9.4)

12 (18.5)

1 (1.4)

 

 Post surgery

25 (18.1)

13 (20)

12 (16.4)

 

 Respiratory failure

27 (19.6)

17 (26.1)

10 (13.7)

 

 Sepsis

39 (28.3)

12 (18.5)

27 (37.0)

 

Parameters on admission to ICU

 APACHE II, mean (SD)

19.4 (6.3)

16.2 (5.1)

22.2 (5.9)

<0.001

 SOFA score, mean (SD)

7.5 (3.7)

6.0 (3.0)

8.9 (3.8)

<0.001

 Lactate (μmol/L), median (IQR)

1.7 (1.1–3.3)

1.4 (0.9–2.1)

1.9 (1.2–4.5)

0.005

 Bilirubin (μmol/L), median (IQR)

10 (7–19)

10 (6–14)

12 (7–30)

0.031

 Sepsis, n (%)

39 (28.3)

12 (18.5)

27 (37.0)

0.016

Parameters in first 24 hours in ICU

 Cumulative fluid balance (ml), median (IQR)

3196 (1606–5166)

2561 (1088–4023)

3730 (2316–5800)

0.002

 No AKI, n (%)

77 (55.8)

–

77 (55.8)

 

 Any stage of AKI, n (%)

    

  1

14 (10.1)

–

14 (10.1)

 

  2

14 (10.1)

–

14 (10.1)

 

  3 without RRT

5 (3.6)

–

5 (3.6)

 

  3 with RRT

28 (20.3)

–

28 (20.3)

 

Outcomes

 MI (in ICU), n (%)

20 (14.5)

9 (13.9)

11 (15.1)

0.839

 Maximum stage of AKI stage during stay in ICU, n (%)

    

  1

13 (9.4)

–

13 (9.4)

 

  2

12 (8.7)

–

12 (8.7)

 

  3 without RRT

8 (5.8)

–

8 (5.8)

 

  3 with RRT

40 (29.0)

–

40 (29.0)

 
  1. APACHE Acute Physiology and Chronic Health Evaluation, AKI acute kidney injury, ICU intensive care unit, IHD ischaemic heart disease, IQR interquartile range, MI myocardial infarction, RRT renal replacement therapy, SD standard deviation, SOFA Sequential Organ Failure Assessment