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Table 2 ICU events and outcomes of ECMO-treated massive PE patients according to 90-day survival status

From: Life-threatening massive pulmonary embolism rescued by venoarterial-extracorporeal membrane oxygenation

Event/outcome

All patients (n = 17)

Non-survivors (n = 9)

Survivors (n = 8)

p

SAPS II at ICU admission

78 (45–95)

83 (71–95)

58 (45–91)

0.04

Shock onset-to-ECMO interval, h

3 (1–24)

3 (1–24)

3.5 (1–12)

0.92

Extracorporeal blood flow during the 1st 24 h, L/min

3.3 (3.0–4.2)

3.3 (3.2–4.2)

3.2 (3.0–3.9)

0.19

SOFA score at ECMO cannulation

12 (8–19)

15 (11–19)

12 (8–15)

0.11

Inotrope score at ECMO cannulation, μg/kg/min

100 (2–760)

75 (2–730)

143 (92–760)

0.17

Inotrope score after 24 h of ECMO, μg/kg/min

50 (0–660)

75 (41–660)

6 (0–51)

0.001

pH ECMO-day 1

7.42 (7.19–7.69)

7.40 (7.19–7.57)a

7.44 (7.32–7.69)

0.79

Blood lactate ECMO-day 1, mmol/L

3.2 (1.1–12.3)

4.5 (1.1–12.3)a

2.3 (1.1–3.5)

0.17

SOFA score

 ECMO-day 1

14 (11–18)

14 (13–18)

12 (11–16)

0.04

 ECMO-day 3

13 (8–18)

15 (12–18)

13 (8–15)

0.03

 ECMO-day 7

6 (1–19)

10 (7–13)

6 (1–19)

0.29

In-ICU complications

 Hemorrhage ≤ GUSTO 2

15 (88)

8 (89)

7 (88)

0.92

 RRT

13 (76)

6 (67)

7 (88)

0.31

 Stroke

4 (24)

1 (11)

3 (38)

0.2

 Surgical wound infection

2 (12)

0

2 (25)

–

 Arterial ischemia

1 (6)

0

1 (12)

–

Packed red-cell units transfused

4 (0–29)

4 (0–6)

9 (0–29)

0.7

Fresh-frozen plasma units transfused

5 (0–11)

3 (0–8)

8 (0–11)

0.7

Tracheotomy

2 (12)

0

2 (25)

–

ECMO duration, days

4 (1–12)

3 (1–13)

4 (3–11)

0.28

MV duration, days

10 (1–43)

3 (1–24)

13 (1–43)

0.03

ICU LOS, days

10 (1–91)

3 (1–24)

17 (7–91)

0.009

Hospital LOS, days

22 (1–135)

6 (1–36)

45 (22–135)

0.004

  1. Categorical variables are expressed as n (%) and continuous variables as median (range)
  2. ICU intensive care unit, ECMO extracorporeal membrane oxygenation, PE pulmonary embolism, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, GUSTO Global Utilization of Streptokinase and TPA for Occluded arteries, RRT renal replacement therapy, MV mechanical ventilation, LOS length of stay
  3. aThree patients died within less than 24 h on ECMO