Table 1 Classification and recommendations for the three antiarrhythmic drugs
From: Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation
Amiodarone | Lidocaine | Nifekalant | |
|---|---|---|---|
Vaughan Williams classification | Class III | Class Ib | Class III |
2015 ILCOR treatment recommendation [5] | Suggest use of amiodarone in adult patients with refractory VF/pVT to improve rates of ROSC. | Suggest use of lidocaine as an alternative to amiodarone in adult patients with refractory VF/pVT. | Suggest use of nifekalant as an alternative to amiodarone in adult patients with refractory VF/pVT. |
Level of recommendation | Weak recommendation, moderate‐quality evidence | Weak recommendation, very‐low‐quality evidence | Weak recommendation, very‐low‐quality evidence |