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Table 1 Characteristics at the time of inclusion or day 1 between survivors and non-survivors at day 90

From: Effect of driving pressure on mortality in ARDS patients during lung protective mechanical ventilation in two randomized controlled trials

Variables All (n = 787) Survivors (n = 533) Nonsurvivors (n = 254) P
Male gender 542 (68.9) 366 (68.7) 176 (69.3) 0.923
Age, years 59 ± 16 56 ± 15 66 ± 14 <0.001
SAPS II on ICU admission 45 ± 15 45 ± 16 51 ± 15 <0.001
SOFA score on day 1 7 ± 4 7 ± 4 9 ± 4 <0.001
Continuous NMBA as allocation group 173 (22.0) 117 (22.0) 56 (22.0) 0.976
Prone position as allocation group 233 (34.4) 181 (34.0) 52 (20.5) <0.001
Arterial pH on day 1 7.35 ± 0.09 7.36 ± 0.08 7.32 ± 0.10 <0.001
PaCO2 on day 1, mmHg 47 ± 11 46 ± 11 47 ± 11 0.076
PaO2/FIO2 ratio on day 1 159 ± 74 163 ± 76 152 ± 68 0.056
Lactate on day 1, mmol/L 2.0 ± 1.9 1.8 ± 1.6 2.4 ± 2.2 <0.001
Respiratory rate on day 1,/minute 27 ± 6 26 ± 5 27 ± 6 0.010
Tidal volume on day 1, ml 397 ± 76 398 ± 76 395 ± 78 0.413
Tidal volume on day 1, ml/PBW kg 6.3 ± 0.8 6.2 ± 0.8 6.3 ± 0.8 0.691
PEEP on day 1, cm H2O 10 ± 3 10 ± 3 10 ± 3 0.210
Plateau pressure on day 1, cm H2O 23 ± 4 23 ± 4 24 ± 4 <0.001
Tidal compliance on day 1, ml/cm H2O 33 ± 12 34 ± 12 31 ± 12 0.016
Driving pressure on day 1, cm H2O 13 ± 4 13 ± 4 14 ± 4 0.002
Mechanical power on day 1, J/min 13.4 ± 5.0 13.0 ± 4.8 14.3 ± 5.4 <0.001
  1. Quantitative values are expressed as mean ± SD and qualitative values are numbers (percentage of group). Tidal compliance of respiratory system was calculated as the ratio of tidal volume to driving pressure. Driving pressure was calculated as the difference between plateau pressure and applied positive end-expiratory pressure (PEEP). Mechanical power was calculated as the product of driving pressure in Newton (cm H2O × 0.098), tidal volume and respiratory rate. Day 1 was defined as the 24 hours following the inclusion. ICU intensive care unit, SAPS II simplified acute physiology score II, SOFA sequential organ failure assessment, PaO 2 /FIO 2 ratio the ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen, PaCO 2 partial pressure of arterial carbon dioxide, PBW predicted body weight, NMBA neuromuscular blocking agent