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Table 5 Adjusted relative risk for hospital mortality by trajectory and KDIGO classification in group 2 (mixed medical-surgical)

From: Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death

    Relative risk (95% CI)
Participants Events, n (%) Model 1 Model 2 Model 3
No AKI 573 62 (10.8) 1.00 (reference) 1.00 (reference)  
KDIGO AKI stage
 Stage 1 944 148 (15.7) 1.27 (0.96–1.69) 1.05 (0.78–1.43)
 Stage 2 165 35 (21.2) 1.75 (1.19–2.57) 1.23 (0.85–1.78)
 Stage 3 185 39 (21.1) 1.68 (1.14–2.48) 1.2 (0.84–1.73)
Subphenotype
 Resolving 875 115 (13.1) 1.05 (0.78–1.43) 0.86 (0.63–1.17) 0.95 (0.64–1.41)
 Nonresolving 419 107 (25.5) 2.04 (1.52–2.75) 1.52 (1.13–2.05) 1.68 (1.15–2.44)
  1. AKI Acute kidney injury, KDIGO Kidney Disease: Improving Global Outcomes
  2. Model 1: Age, sex, race
  3. Model 2: Body mass index, diabetes mellitus, Sepsis-related Organ Failure Assessment score, vasopressor use, sepsis
  4. Model 3: Maximum KDIGO stage of AKI