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Table 5 Adjusted relative risk for hospital mortality by trajectory and KDIGO classification in group 2 (mixed medical-surgical)

From: Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death

   

Relative risk (95% CI)

Participants

Events, n (%)

Model 1

Model 2

Model 3

No AKI

573

62 (10.8)

1.00 (reference)

1.00 (reference)

 

KDIGO AKI stage

 Stage 1

944

148 (15.7)

1.27 (0.96–1.69)

1.05 (0.78–1.43)

 Stage 2

165

35 (21.2)

1.75 (1.19–2.57)

1.23 (0.85–1.78)

 Stage 3

185

39 (21.1)

1.68 (1.14–2.48)

1.2 (0.84–1.73)

Subphenotype

 Resolving

875

115 (13.1)

1.05 (0.78–1.43)

0.86 (0.63–1.17)

0.95 (0.64–1.41)

 Nonresolving

419

107 (25.5)

2.04 (1.52–2.75)

1.52 (1.13–2.05)

1.68 (1.15–2.44)

  1. AKI Acute kidney injury, KDIGO Kidney Disease: Improving Global Outcomes
  2. Model 1: Age, sex, race
  3. Model 2: Body mass index, diabetes mellitus, Sepsis-related Organ Failure Assessment score, vasopressor use, sepsis
  4. Model 3: Maximum KDIGO stage of AKI