Fig. 3

ROC curves to describe the relationship between the plasmatic concentration of mid-regional pro-adrenomedullin (MR-proADM) and fluid overload of 4 L for ∆H₂O and 36 g for ∆Na⁺. Area under the curve (AUC) is 0.838 (0.780–0.888) for ∆H₂O and 0.823 (0.764–0.880) for ∆Na⁺ determining the relationship between dangerous fluid overload and plasmatic MR-proADM. The Youden index indicates a threshold for plasmatic MR-proADM (0.865 nmol/L (specificity 0.625/sensitivity 0.865) for ∆Na⁺ >36 g and 1.125 nmol/L (specificity 0.900/sensitivity 0.604) for ∆H₂O >4 L) to predict fluid overload