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Table 3 Haemodynamic variables during PLR

From: Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal

     P values
  Before PLR During PLR % Change from baseline During PLR vs. before PLR Failed SBT vs. succeeded SBT before PLR Failed SBT vs. succeeded SBT during PLR Cases without WiPO vs. cases with WiPO before PLR Cases without WiPO vs. cases with WiPO during PLR
Heart rate (beats/min)
 Succeeded SBT (n = 40) 84 ± 17 86 ± 16 4 ± 10 % 0.03     
 Failed SBT (n = 45) 91 ± 18 94 ± 19 3 ± 10 % 0.06 0.05 0.04   
  Cases with WiPO (n = 30) 90 ± 16 93 ± 17 4 ± 12 % 0.15     
  Cases without WiPO (n = 15) 94 ± 22 96 ± 22 3 ± 6 % 0.07    0.49 0.59
Systolic arterial pressure (mmHg)
 Succeeded SBT (n = 40) 133 ± 24 141 ± 23 6 ± 8 % <0.01     
 Failed SBT (n = 45) 125 ± 20 130 ± 21 5 ± 10 % <0.01 0.10 0.04   
  Cases with WiPO (n = 30) 129 ± 18 135 ± 18 6 ± 8 % <0.01     
  Cases without WiPO (n = 15) 117 ± 23 120 ± 25 3 ± 12 % 0.35    0.07 0.03
Mean arterial pressure (mmHg)
 Succeeded SBT (n = 40) 89 ± 16 95 ± 17 8 ± 10 % <0.01     
 Failed SBT (n = 45) 86 ± 12 91 ± 13 6 ± 11 % <0.01 0.40 0.18   
  Cases with WiPO (n = 30) 88 ± 12 94 ± 12 7 ± 9 % <0.01     
  Cases without WiPO (n = 15) 83 ± 14 85 ± 12 3 ± 14 % 0.53    0.24 0.03
Diastolic arterial pressure (mmHg)
 Succeeded SBT (n = 40) 64 ± 12 68 ± 12 7 ± 12 % 0.05     
 Failed SBT (n = 45) 64 ± 9 69 ± 10 9 ± 12 % <0.01 0.79 0.85   
  Cases with WiPO (n = 30) 64 ± 9 71 ± 10 11 ± 11 % <0.01     
  Cases without WiPO (n = 15) 63 ± 9 65 ± 9 4 ± 13 % 0.36    0.79 0.09
Cardiac index (L/min/m2)
 Succeeded SBT (n = 40) 3.4 ± 0.7 3.7 ± 0.7 15 ± 13 % <0.01     
 Failed SBT (n = 45) 3.5 ± 0.8 3.8 ± 1.0 7 ± 16 % 0.01 0.24 0.64   
  Cases with WiPO (n = 30) 3.7 ± 0.9 3.8 ± 0.9 3 ± 7 % 0.06     
  Cases without WiPO (n = 15) 3.2 ± 0.6 3.7 ± 1.2 17 ± 24 % 0.02    0.03 0.60
Cases with increase in cardiac index ≥10 % during PLR
 Succeeded SBT (n = 40)   28 (70 %)       
 Failed SBT (n = 45)   10 (22 %)     <0.01   
  Cases with WiPO (n = 30)   2 (7 %)       
  Cases without WiPO (n = 15)   8 (53 %)       <0.01
  1. Values are expressed as mean ± standard deviation or number and frequency (%)
  2. PLR passive leg raising, SBT spontaneous breathing trial, WiPO weaning-induced pulmonary oedema