Fig. 9 (abstract P9).

Patients that progressed into having hypotension, azotemia or thrombocytopenia have significantly higher histone levels than those that did not. In this cohort, those that progressed to severe sepsis (Mean = 2110, 95 % CI 2095–2125) have significantly higher levels of histones in their blood (P < 0.05, two-tailed t-test), as compared to those who did not progress (Mean = 2084, 95 % CI 2073–2096)