Table 3 Subgroup analysis of characteristics of patients extubated after >72 h of mechanical ventilation
Characteristics | All patients (n = 160) | Phase I (n = 94) | Phase II (n = 66) | P value |
|---|---|---|---|---|
Age, years | 58.5 ± 15.9 | 58.4 ± 17.4 | 58.7 ± 13.7 | 0.879 |
Female sex, n (%) | 59 (36.9) | 35 (37.2) | 24 (36.4) | 1.000 |
APACHE II score | 27.6 ± 8.9 | 26.7 ± 8.9 | 29.0 ± 8.7 | 0.111 |
Weight, kg | 67.0 ± 19.8 | 68.0 ± 21.4 | 65.7 ± 17.3 | 0.472 |
Ventilator days preextubation | 6 (4–8) | 6 (4–9) | 6 (4–8) | 0.807 |
Main diagnosis, n (%) | 0.128 | |||
Pneumonia | 53 (33.1) | 27 (28.7) | 26 (39.4) | |
Nonpneumonia sepsis | 21 (13.1) | 10 (10.6) | 11 (16.7) | |
COPD | 6 (3.8) | 2 (2.1) | 4 (6.1) | |
Asthma | 9 (5.6) | 5 (5.3) | 4 (6.1) | |
Fluid overload | 13 (8.1) | 8 (8.5) | 5 (7.6) | |
Stroke | 6 (3.8) | 6 (6.4) | 0 (0.0) | |
Seizure | 10 (6.3) | 8 (8.5) | 2 (3.0) | |
Othera | 42 (26.3) | 28 (29.8) | 14 (21.2) | |
Comorbidity, n (%) | ||||
Diabetes mellitus | 66 (41.5) | 34 (36.6) | 32 (48.5) | 0.145 |
Hypertension | 86 (54.1) | 51 (54.8) | 35 (53.0) | 0.872 |
IHD | 41 (25.8) | 25 (26.9) | 16 (24.2) | 0.854 |
CHF | 8 (5.0) | 3 (3.2) | 5 (7.6) | 0.278 |
Asthma | 23 (14.5) | 11 (11.8) | 12 (18.2) | 0.360 |
COPD | 8 (5.0) | 2 (2.2) | 6 (9.1) | 0.067 |
Bronchiectasis | 3 (1.9) | 0 (0.0) | 3 (4.6) | 0.070 |
OSA | 11 (6.9) | 7 (7.5) | 4 (6.1) | 1.000 |
CKD | 36 (22.6) | 18 (19.4) | 18 (27.3) | 0.254 |
CLD | 6 (3.8) | 4 (4.3) | 2 (3.0) | 1.000 |
Stroke | 19 (12.0) | 14 (15.1) | 5 (7.6) | 0.215 |
Cancer | 17 (10.7) | 9 (9.7) | 8 (12.1) | 0.615 |