Fig. 2
From: Use of explicit ICD9-CM codes to identify adult severe sepsis: impacts on epidemiological estimates
Trends in age-adjusted incidence of severe sepsis according to assigned ICD-9-CM codes. Values are adjusted annual rates. In the explicit code cohort, adjusted incidence rates increased from 36 cases per 100 000 inhabitants in 2006 to 73.6 per 100 000 in 2011, and from 34.6 to 40.9 cases per 100,000 inhabitants in the combination code cohort. Within the cohort of explicit codes, the adjusted incidence rate of cases assigned code 785.52 (septic shock) rose from 28.6 to 46.5 cases per 100 000 inhabitants, while cases identified using 995.92 (severe sepsis) rose from 7.4 to 27.3 cases per 100 000 inhabitants