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Table 4 Multivariable analysis to identify independent risk factors for reintubation at 72 h and 7 days postextubation, and for death at 90 days postextubation, in patients with chronic obstructive pulmonary disease

From: Noninvasive ventilation for avoidance of reintubation in patients with various cough strength

  Cough peak flow ≤ 70 L/minute Cough peak flow > 70 L/minute
OR (95 % CI) p Value OR (95 % CI) p Value
Reintubation at 72 h postextubation
 Use of NIV 0.11 (0.03–0.38) <0.01 N/A
 Intubation period before extubation, days 1.10 (1.01–1.09) 0.03 N/A
Reintubation at 7 days postextubation
 Use of NIV 0.27 (0.10–0.77) 0.01 N/A
 Cough peak flow, L/minute 0.95 (0.92–0.98) <0.01 N/A
Death at 90 days postextubation
 Use of NIV 0.27 (0.10–0.74) 0.01 N/A
 Hemoglobin, g/dl 0.98 (0.95–1.00) 0.02 0.97 (0.93–1.00) 0.05
 Cough peak flow, L/minute 0.97 (0.94–1.00) 0.03 N/A
 APACHE II score at extubation 1.21 (1.01–1.46) 0.04 1.46 (1.03–2.07) 0.04
  1. NIV Noninvasive ventilation, APACHE II Acute Physiology and Chronic Health Evaluation II, N/A Not applicable
  2. We entered age, sex, APACHE II score, intubation periods, cough peak flow, hemoglobin, secretions, suction frequency, Glasgow Coma Scale score, heart rate, respiratory rate, rapid shallow breathing index, arterial blood gas tests, and use of NIV into multivariable analysis to identify independent risk factors for reintubation at 72 h and 7 days postextubation, and for death at 90 days postextubation