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Table 2 Proposed criteria for choosing between pharmacological and non-pharmacological antipyretic methods

From: Should we treat pyrexia? And how do we do it?

Antipyretic agents

Physical cooling

• Non sedated patients

• Concomitant need for analgesia

• Hypothalamic dysfunction

• Need for rapid induction

• Need for strict temperature control

• Patients with hemodynamic instability

• Failure of antipyretic agents