Fig. 1From: Nonvitamin K antagonist oral anticoagulant activity: challenges in measurement and reversalSites of action of prothrombin complex concentrates, nonvitamin K antagonist oral anticoagulants, and warfarin on the coagulation cascade. Blue boxes indicate factors that are present in 3Â F- and 4Â F-PCCs; the red box indicates factor present in 4Â F-PCCs. 3Â F-PCC 3-factor prothrombin complex concentrate, 4Â F-PCC 4-factor prothrombin complex concentrateBack to article page