Table 3 Bleeding complications in subsets stratified according to baseline SOFA scores
From: Benefit profile of anticoagulant therapy in sepsis: a nationwide multicentre registry in Japan
| Â | Anticoagulant group | Control group | OR (95Â % CI) | P value |
|---|---|---|---|---|
Transfusion related to bleeding | ||||
 SOFA score ≤7 | 36/274 (13 %) | 40/665 (6 %) | 1.414 (0.817, 2.447) | 0.216 |
 SOFA score 8–12 | 84/615 (14 %) | 42/554 (8 %) | 1.306 (0.836, 2.041) | 0.241 |
 SOFA score 13–17 | 55/328 (17 %) | 14/177 (8 %) | 1.739 (0.886, 3.412) | 0.108 |
 SOFA score ≥18 | 8/30 (27 %) | 2/20 (10 %) | 9.516 (0.861, 105.193) | 0.066 |
Intracranial haemorrhage | ||||
 SOFA score ≤7 | 3/274 (1 %) | 1/665 (0.2 %) | 6.142 (0.501, 75.288) | 0.156 |
 SOFA score 8–12 | 3/615 (0.5 %) | 2/554 (0.4 %) | 0.608 (0.080, 4.600) | 0.630 |
 SOFA score 13–17 | 1/328 (0.3 %) | 1/177 (0.6 %) | 0.286 (0.016, 5.268) | 0.400 |
 SOFA score ≥18 | 0/20 (0 %) | 0/30 (0 %) | - | - |
Surgical interventions | ||||
 SOFA score ≤7 | 3/274 (1 %) | 1/665 (0.2 %) | 7.634 (0.642, 90.792) | 0.108 |
 SOFA score 8–12 | 10/615 (2 %) | 7/554 (1 %) | 1.001 (0.326, 3.074) | 0.998 |
 SOFA score 13–17 | 7/328 (2 %) | 3/177 (2 %) | 0.824 (0.188, 3.608) | 0.797 |
 SOFA score ≥18 | 1/30 (3 %) | 0/20 (0 %) | - | - |