Table 1 Patient characteristics in the overall population and in relation to adrenaline use
All (n = 216) | Patients treated with adrenaline (n = 46) | Patients not treated with adrenaline (n = 170) | P | |
|---|---|---|---|---|
Age, mean (SD) | 66.6 (11.8) | 67.7 (9.4) | 66.3 (12.4) | 0.4 |
Women, % | 26 % | 28 % | 25 % | 0.7 |
Medical history, % | ||||
Coronary artery disease | 35 % | 44 % | 32 % | 0.16 |
Previous MI | 25 % | 30 % | 23 % | 0.3 |
Previous PCI | 15 % | 15 % | 14 % | 0.9 |
Previous CABG | 7 % | 9 % | 7 % | 0.7 |
Heart failure | 17 % | 15 % | 17 % | 0.8 |
Hypertension | 60 % | 67 % | 58 % | 0.3 |
Diabetes | 28 % | 35 % | 26 % | 0.2 |
Renal insufficiency | 12 % | 20 % | 9 % | 0.051 |
Atrial fibrillation/flutter | 15 % | 17 % | 14 % | 0.5 |
Clinical presentation | ||||
ACS etiology | 81 % | 87 % | 79 % | 0.2 |
Blood pressure, mmHg | ||||
Systolic | 78 (14) | 77 (15) | 78 (14) | 0.9 |
Diastolic | 47 (10) | 44 (13) | 47 (9) | 0.1 |
Mean arterial pressure | 57 (11) | 55 (12) | 57 (10) | 0.3 |
Heart rate, beats/minute | 90 (28) | 96 (29) | 89 (28) | 0.15 |
Sinus rhythm | 77 % | 72 % | 79 % | 0.3 |
Clinical findings | ||||
Cold periphery | 95 % | 98 % | 94 % | 0.3 |
Confusion | 68 % | 96 % | 61 % | <0.001 |
Oliguria | 57 % | 82 % | 49 % | <0.001 |
Lactate >2 mmol/l | 72 % | 93 % | 66 % | <0.001 |
Resuscitation before enrolment | 28 % | 39 % | 25 % | 0.07 |
LVEF, %, mean (SD) | 33 (14) | 31 (15) | 34 (14) | 0.3 |
Biochemistry | ||||
Hemoglobin, g/l | 128 (22) | 130 (22) | 128 (22) | 0.7 |
Creatinine, μmol/l | 105 (80-139) | 134 (91-171) | 99 (80-135) | 0.001 |
eGFR, ml/min/1.73 m2 | 60 (41–85) | 45 (30–60) | 64 (44–88) | <0.001 |
<60 ml/min/1.73 m2 | 50 % | 76 % | 43 % | <0.001 |
Lactate, mmol/l | 2.9 (1.7–5.8) | 5.6 (3.2–8.8) | 2.5 (1.5–4.4) | <0.001 |
HsTnT, ng/l | 2190 (393–5419) | 2529 (463–4537) | 2096 (357–6624) | 0.8 |
NT-proBNP, ng/l | 2710 (599–9583) | 2088 (580–15753) | 2995 (592–9133) | 0.8 |