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Table 5 Risk factors for ventilator-associated pneumonia by Cox proportional hazards model

From: Hyperoxemia as a risk factor for ventilator-associated pneumonia

Variable Univariate analysis Multivariate analysis (model 1) Multivariate analysis (model 2)
HR (95 % CI) P HR (95 % CI) P HR (95 % CI) P
At ICU admission       
 LOD score 1.04 (1.01, 1.09) 0.044 - 0.922 - 0.138
 Transfer from other wards 0.65 (0.45, 0.93) 0.018 - 0.356 - 0.952
 Prior antibiotic treatment 0.67 (0.48, 0.94) 0.021 - 0.483 - 0.184
 Neurologic failure 1.82 (1.07, 3.09) 0.027 - 0.111 - 0.197
 Poisoning 3.24 (1.9, 5.51) <0.001 2.49 (1.31, 4.72) 0.005 2.16 (1.14, 4.09) 0.018
 COPD 0.55 (0.37, 0.89) 0.003 - 0.063 - 0.065
 McCabe score >2 0.76 (0.59, 0.99) 0.042 - 0.169   0.726
 PaO2 > 120 mmHg 1.58 (1.11, 2.25) 0.011 NA NA 1.68 (1.16, 2.42) 0.006
During ICU stay       
 Percentage of days with PaO2 > 120 mmHg 5.67 (3.15, 10.20) <0.001 6.23 (3.26, 11.9) <0.001 NA NA
  1. HR hazard ratio, LOD logistic organ dysfunction, COPD chronic obstructive pulmonary disease, NA not applicable. P > 0.1 by univariate analysis for: age, male gender, simplified acute physiology score II, diabetes, cardiac failure, cirrhosis, chronic dialysis, immunosuppression, all causes of ICU admission except neurologic failure, stress ulcer prophylaxis, tracheostomy, red blood cell transfusion, sedation, and neuromuscular-blocking agent use