Table 3 Clinical and demographic characteristics of septic shock patients
At D1 according to survival at D7 | At D3 according to survival at D28 | |||||
|---|---|---|---|---|---|---|
Characteristics | Total (n = 279) | Survivors (n = 222) | Non-survivors (n = 57) | Total (n = 192) | Survivors (n = 146) | Non-survivors (n = 46) |
Age, years | 67 [58–77] | 67 [57–77] | 69 [62–77] | 67 [57–78] | 67 [56–77] | 73 [62–79] |
Male sex | 171 (61.3 %) | 140 (63.1 %) | 31 (54.4 %) | 122 (63.5 %) | 91 (62.3 %) | 31 (67.4 %) |
SAPS II | 64 [52–78] | 59 [48–71] | 88 [70–98] | 60 [50–73] | 58 [48–70] | 68 [57–80] |
SOFA score at D1 | 11 [9–13] | 10 [8–12] | 14 [12–16] | 8 [5–12] | 8 [4–11] | 12 [8–15] |
Charlson comorbidity index score | 2 [1–3] | 2 [1–3] | 2 [1–4] | 2 [1–3] | 2 [1–3] | 3 [1–4] |
Lactic acid, mmol/La | 2.6 [1.8–5.2] | 2.5 [1.7–3.9] | 4.8 [2.7–8.8] | 1.6 [1.2–2.2] | 2.2 [1.6–3.4] | 3.1 [1.9–6.1] |
Respiratory supportb | 243 (87.1 %) | 187 (84.2 %) | 56 (98.1 %) | 157 (81.8 %) | 117 (80.1 %) | 40 (87.0 %) |
Diagnostic category | ||||||
Medical | 184 (65.9 %) | 144 (64.9 %) | 40 (70.2 %) | 127 (66.1 %) | 98 (67.1 %) | 29 (63.0 %) |
Planned surgery | 10 (3.6 %) | 10 (4.5 %) | 0 (0.0 %) | 6 (3.1 %) | 5 (3.4 %) | 1 (2.2 %) |
Urgent surgery | 85 (30.5 %) | 68 (30.6 %) | 17 (29.8 %) | 59 (30.7 %) | 43 (29.4 %) | 16 (34.8 %) |
Type of sepsis acquisition | ||||||
Community-acquired | 169 (60.6 %) | 135 (60.8 %) | 34 (59.6 %) | 114 (59.4 %) | 92 (63.0 %) | 22 (47.8 %) |
Hospital-acquired | 110 (39.4 %) | 87 (39.2 %) | 23 (40.4 %) | 78 (40.6 %) | 54 (37.0 %) | 24 (52.2 %) |
Site of infection | ||||||
Respiratory | 130 (46.6 %) | 107 (48.2 %) | 23 (40.4 %) | 92 (47.9 %) | 72 (49.3 %) | 20 (43.5 %) |
Abdominal | 67 (24.0 %) | 49 (22.1 %) | 18 (31.6 %) | 43 (22.4 %) | 27 (18.5 %) | 16 (34.8 %) |
Others | 82 (29.4 %) | 66 (29.7 %) | 16 (28.0 %) | 57 (29.6 %) | 47 (32.2 %) | 10 (21.7 %) |
Type of detection | ||||||
Clinical + imaging | 55 (19.7 %) | 43 (19.4 %) | 12 (21.1 %) | 39 (20.3 %) | 27 (18.5 %) | 12 (26.1 %) |
Clinical + surgery | 15 (5.4 %) | 9 (4.1 %) | 6 (10.5 %) | 8 (4.2 %) | 5 (3.4 %) | 3 (6.5 %) |
Microbiology | 198 (71 %) | 160 (72.1 %) | 38 (66.7 %) | 136 (70.8 %) | 106 (72.6 %) | 30 (65.2 %) |
Suspected | 11 (3.9 %) | 10 (4.5 %) | 1 (1.8 %) | 9 (4.7 %) | 8 (5.5 %) | 1 (2.2 %) |