Table 1 Patient characteristics at intensive care unit admission
All patients (n = 71) | Nongradual VAP (n = 28) | Gradual VAP (n = 43) | p Value | |
|---|---|---|---|---|
Age, years | 61 [53–71.5] | 60 [54.5–73] | 63 [50–71] | 0.874 |
Male sex | 45 (63 %) | 15 (53 %) | 30 (70 %) | 0.166 |
Smoking | 29 (41 %) | 9 (32 %) | 20 (46 %) | 0.229 |
Alcohol | 14 (20 %) | 9 (32 %) | 5 (12 %) | 0.034 |
APACHE II score | 23 [18.5–28.5] | 21.5 [18.5–25.5] | 25 [18.5–31.5] | 0.166 |
Comorbidities | ||||
Hypertension | 32 (45 %) | 12 (43 %) | 20 (46 %) | 0.762 |
Diabetes mellitus | 17 (24 %) | 8 (28 %) | 9 (21 %) | 0.461 |
Chronic cardiac failure | 3 (4 %) | 0 | 3 (7 %) | 0.171 |
Chronic renal failure | 8 (11 %) | 2 (7 %) | 6 (14 %) | 0.466 |
Chronic lung disease/COPD | 11 (15 %) | 3 (11 %) | 8 (19 %) | 0.469 |
Immunosuppression | 22 (31 %) | 8 (29 %) | 14 (32 %) | 0.723 |
Reason for intubation | ||||
Respiratory failure | 29 (41 %) | 11 (39 %) | 18 (42 %) | 0.754 |
Cardiovascular failure | 12 (17 %) | 5 (18 %) | 7 (16 %) | 0.488 |
Coma | 30 (42 %) | 12 (43 %) | 18 (42 %) | 0.813 |
SOFA | 11 [7.5–12.5] | 11 [7–13] | 11 [8–12] | 0.928 |
CPIS | 4 [3.5–5] | 4 [3.5–5] | 4 [3–5] | 0.431 |
PaO2/FiO2 | 195 [100–250] | 175 [120.5–250] | 200 [69.5–250] | 0.816 |
Temperature, °C | 36.3 [36–36.9] | 36.2 [36–36.9] | 36.5 [36–36.9] | 0.815 |
Leukocytes, cells/mm3 | 11,100 [9150–14,900] | 11,100 [10600–12,300] | 11,750 [8500–20,800] | 0.729 |
CRP, mg/L | 28 [0.5–104] | 111 [6–250] | 19 [0.5–70.2] | 0.165 |
PCT, ng/ml | 0.26 [0.01–1.44] | 0.39 [0.01–1.44] | 0.17 [0.01–0.76] | 0.743 |