Variable | Caucasians with DNA (n = 320) | Caucasians without DNA (n = 321) | p Value |
---|---|---|---|
Age, years, mean ± SD | 50 ± 16 | 52 ± 16 | 0.06 |
Male sex, % | 51Â % | 51Â % | 0.96 |
APACHE III score, mean ± SD | 92 ± 29 | 92 ± 31 | 0.77 |
Clinical disorders associated with acute lung injury | Â | Â | Â |
 Pneumonia, % | 46 % | 47 % | 0.78 |
 Trauma, % | 8 % | 5 % | 0.15 |
 Sepsis, % | 21 % | 25 % | 0.26 |
 Multiple transfusions, % | 2 % | 1 % | 0.25 |
 Aspiration, % | 17 % | 17 % | 0.90 |
 Baseline PaO2/FiO2 | 103 ± 48 | 106 ± 49 | 0.45 |
Severity of ARDS | Â | Â | 0.36 |
 Mild | 59 % | 53 % |  |
 Moderate | 36 % | 41 % |  |
 Severe | 5 % | 6 % |  |
Day 1 PIP | 32 ± 8 | 32 ± 9 | 0.32 |
Day 1 PEEP | 9.4 ± 4 | 9.5 ± 4 | 0.7 |
Fluid management, liberal, % | 48Â % | 55Â % | 0.09 |
Mortality at 60Â days, % | 21Â % | 25Â % | 0.19 |
Ventilator-free days, median (range) | 19 (0–28) | 17 (0–28) | 0.22 |