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Table 1 Characteristics of patients from the Fluid and Catheter Treatment Trial

From: Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome

Variable Caucasians with DNA (n = 320) Caucasians without DNA (n = 321) p Value
Age, years, mean ± SD 50 ± 16 52 ± 16 0.06
Male sex, % 51 % 51 % 0.96
APACHE III score, mean ± SD 92 ± 29 92 ± 31 0.77
Clinical disorders associated with acute lung injury    
 Pneumonia, % 46 % 47 % 0.78
 Trauma, % 8 % 5 % 0.15
 Sepsis, % 21 % 25 % 0.26
 Multiple transfusions, % 2 % 1 % 0.25
 Aspiration, % 17 % 17 % 0.90
 Baseline PaO2/FiO2 103 ± 48 106 ± 49 0.45
Severity of ARDS    0.36
 Mild 59 % 53 %  
 Moderate 36 % 41 %  
 Severe 5 % 6 %  
Day 1 PIP 32 ± 8 32 ± 9 0.32
Day 1 PEEP 9.4 ± 4 9.5 ± 4 0.7
Fluid management, liberal, % 48 % 55 % 0.09
Mortality at 60 days, % 21 % 25 % 0.19
Ventilator-free days, median (range) 19 (0–28) 17 (0–28) 0.22
  1. APACHE Acute Physiology and Chronic Health Evaluation, ARDS acute respiratory distress syndrome, FiO 2 fraction of inspired oxygen, PaO 2 partial pressure of arterial oxygen, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure