Table 3 Clinical characteristics upon emergency room admission of trauma patients (2012–2014) with and without tranexamic acid administered during the prehospital phase
From: Prehospital administration of tranexamic acid in trauma patients
Tranexamic acid (TXA) group | Control group | p Value | |
|---|---|---|---|
SBP at ER ≤90 mmHg, n (%) | 51/236 (21.6) | 50/247 (20.2) | 0.74 |
SBP at ER, mmHg, mean ± SD (n) | 114 ± 27 (236) | 117 ± 32 (247) | 0.19 |
Haemoglobin,a g/dl, mean ± SD (n) | 11.7 ± 2.8 (239) | 11.4 ± 2.8 (227) | 0.33 |
Base excess,a mmol/L, mean ± SD (n) | −3.1 ± 4.7 (221) | −3.5 ± 5.1 (219) | 0.38 |
INR,a mean ± SD (n) | 1.3 ± 0.7 (230) | 1.3 ± 0.5 (216) | 0.53 |
PTI,a Quick’s test points, mean ± SD (n) | 76 ± 22 (230) | 75 ± 23 (216) | 0.57 |
i.v. Fluids,b ml, mean ± SD (n) | 1945 ± 2889 (182) | 1867 ± 2005 (146) | 0.46 |
Crystalloids,b ml, mean ± SD (n) | 1668 ± 2421 (182) | 1523 ± 1817 (146) | 0.92 |
Colloids,b ml, mean ± SD (n) | 249 ± 591 (182) | 317 ± 556 (146) | 0.18 |
pRBC transfusion,b n (%) | 64/258 (24.8) | 65/258 (25.2) | 1.00 |
pRBC units,b mean ± SD (n) | 1.6 ± 4.3 (258) | 2.0 ± 5.8 (258) | 0.81 |
Number of units if given, mean ± SD/median | 6.6 ± 6.5/4 | 7.8 ± 9.4/4 | 0.81 |
FFP transfusion,b n (%) | 40/258 (15.5) | 43/258 (16.7) | 0.81 |
FFP units,b mean ± SD (n) | 1.2 ± 3.8 (258) | 1.4 ± 4.6 (258) | 0.68 |
Number of units if given, mean ± SD/median | 7.7 ± 6.7/6 | 8.4 ± 8.1/5 | 0.68 |
Platelet transfusion,b n (%) | 8/258 (3.1) | 12/256(4.7) | 0.37 |
Platelet units,b mean ± SD (n) | 0.1 ± 0.7 (258) | 0.1 ± 0.9 (256) | 0.37 |
Number of units if given, mean ± SD/median | 3.8 ± 2.1/3.5 | 2.9 ± 3.0/2 | 0.37 |
Massive transfusion,b ≥10 pRBC, n (%) | 13/258 (5.0) | 15/258 (5.8) | 0.85 |
Haemostatic drugs,b n (%) | 36/205 (17.6) | 35/149 (23.5) | 0.18 |
Fibrinogen concentrate,b n (%) | 26/205 (12.7) | 24/149 (16.1) | 0.44 |
Level 1 trauma centre, n (%) | 182/258 (70.5) | 200/258 (77.5) | 0.09 |