From: Prehospital administration of tranexamic acid in trauma patients
Tranexamic acid (TXA) group (n = 258) | Control group (n = 258) | p Value | |
---|---|---|---|
Age, years, mean ± SD | 43 ± 19 | 41 ± 18 | 0.48 |
Male sex, n (%) | 187 (72.5) | 187 (72.5) | 1.00 |
Traffic accident, n (%) | 180 (69.8) | 189 (73.3) | 0.44 |
Blunt trauma, n (%) | 233 (90.3) | 240 (93.0) | 0.34 |
ISS, points, mean ± SD | 24 ± 14 | 24 ± 16 | 0.46 |
AIShead ≥3, n (%) | 89 (34.5) | 95 (36.8) | 0.65 |
AISthorax ≥3, n (%) | 120 (46.5) | 125 (48.4) | 0.72 |
AISabdomen ≥3 n (%) | 54 (20.9) | 47 (18.2) | 0.51 |
AISextremities ≥3, n (%) | 114 (44.2) | 112 (43.4) | 0.93 |
Isolated TBI, AIShead ≥3, n (%) | 7 (2.7) | 8 (3.1) | 0.94 |
SBP at scene ≤90 mmHg, n (%) | 55 (21.3) | 54 (20.9) | 1.0 |
SBP at scene, mmHg, mean ± SD | 118 ± 34 | 116 ± 33 | 0.36 |
GCS at scene ≤8, n (%) | 89 (34.5) | 96 (37.2) | 0.58 |
GCS at scene, points, mean ± SD | 10.5 ± 4.9 | 10.2 ± 5.0 | 0.69 |
Prehospital treatment | |||
Intubation, n (%) | 193 (74.8) | 195 (75.6) | 0.92 |
Chest tube insertion, n (%) | 34 (13.2) | 28 (10.9) | 0.50 |
CPR, n (%) | 11 (4.3) | 8 (3.1) | 0.64 |
Catecholamines, n (%) | 44 (17.1) | 50 (19.4) | 0.57 |
i.v. Fluids, ml, mean ± SD | 1140 ± 760 | 1181 ± 919 | 0.84 |
Duration of prehospital phase, minutes, mean ± SD | 77.2 ± 25.0 | 74.2 ± 25.1 | 0.22 |
Air transport, n (%) | 210 (81.4) | 203 (78.7) | 0.51 |