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Table 2 Demographic and prehospital characteristics of trauma patients (2012–2014) with and without tranexamic acid administered during the prehospital phase

From: Prehospital administration of tranexamic acid in trauma patients

  Tranexamic acid (TXA) group (n = 258) Control group (n = 258) p Value
Age, years, mean ± SD 43 ± 19 41 ± 18 0.48
Male sex, n (%) 187 (72.5) 187 (72.5) 1.00
Traffic accident, n (%) 180 (69.8) 189 (73.3) 0.44
Blunt trauma, n (%) 233 (90.3) 240 (93.0) 0.34
ISS, points, mean ± SD 24 ± 14 24 ± 16 0.46
AIShead ≥3, n (%) 89 (34.5) 95 (36.8) 0.65
AISthorax ≥3, n (%) 120 (46.5) 125 (48.4) 0.72
AISabdomen ≥3 n (%) 54 (20.9) 47 (18.2) 0.51
AISextremities ≥3, n (%) 114 (44.2) 112 (43.4) 0.93
Isolated TBI, AIShead ≥3, n (%) 7 (2.7) 8 (3.1) 0.94
SBP at scene ≤90 mmHg, n (%) 55 (21.3) 54 (20.9) 1.0
SBP at scene, mmHg, mean ± SD 118 ± 34 116 ± 33 0.36
GCS at scene ≤8, n (%) 89 (34.5) 96 (37.2) 0.58
GCS at scene, points, mean ± SD 10.5 ± 4.9 10.2 ± 5.0 0.69
Prehospital treatment    
 Intubation, n (%) 193 (74.8) 195 (75.6) 0.92
 Chest tube insertion, n (%) 34 (13.2) 28 (10.9) 0.50
 CPR, n (%) 11 (4.3) 8 (3.1) 0.64
 Catecholamines, n (%) 44 (17.1) 50 (19.4) 0.57
 i.v. Fluids, ml, mean ± SD 1140 ± 760 1181 ± 919 0.84
Duration of prehospital phase, minutes, mean ± SD 77.2 ± 25.0 74.2 ± 25.1 0.22
Air transport, n (%) 210 (81.4) 203 (78.7) 0.51
  1. AIS Abbreviated Injury Scale, CPR cardiopulmonary resuscitation, GCS Glasgow Coma Scale, i.v. intravenous, ISS Injury Severity Score, SBP systolic blood pressure, SD standard deviation, TBI traumatic brain injury
  2. Data for all 516 patients were documented for the parameters of this table