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Table 1 Multivariable analysis using a logistic regression model with prehospital administration of tranexamic acid as a dependent variable (n = 5765)

From: Prehospital administration of tranexamic acid in trauma patients

Variable entered Regression coefficient β OR (eβ; 95 % CI) p Value
Isolated TBI (AIShead ≥3) −1.009 0.365 (0.165–0.806) 0.013
AISthorax ≥3 −0.282 0.755 (0.570–0.998) 0.049
AISabdomen ≥3 0.524 1.689 (1.212–2.355) 0.002
AISextremities ≥3 0.346 1.414 (1.078–1.854) 0.012
Intubation prehospital 1.043 2.837 (2.022–3.981) <0.001
Chest tube prehospital 0.506 1.658 (1.093–2.516) 0.017
Penetrating injury 0.369 1.446 (0.970–2.157) 0.070
Prehospital i.v. fluids ≥1000 ml 0.147 1.159 (0.980–1.370) 0.085
Initial systolic blood pressure    
  > 110 mmHg Reference   0.193
 81–110 mmHg −1.164 0.312 (0.074–1.321) 0.114
 1–80 mmHg 0.244 1.276 (0.843–1.930) 0.249
 0 mmHg 0.141 1.152 (0.849–1.563) 0.364
Age ≥60 years −0.397 0.672 (0.477–0.947) 0.023
Prehospital GCS score ≤8 −0.166 0.847 (0.630–1.140) 0.275
Constant* −3.791 0.023 <0.001
  1. AIS Abbreviated Injury Scale, GCS Glasgow Coma Scale, i.v. intravenous, TBI traumatic brain injury
  2. The reference category is included in brackets behind the variable name and does not receive a coefficient in the model. ORs have to be interpreted in relation to this standard category
  3. *The constant in a logistic model provides a basic risk that applies to the case that all other coefficients are zero