Table 1 Multivariable analysis using a logistic regression model with prehospital administration of tranexamic acid as a dependent variable (n = 5765)
From: Prehospital administration of tranexamic acid in trauma patients
Variable entered | Regression coefficient β | OR (eβ; 95 % CI) | p Value |
|---|---|---|---|
Isolated TBI (AIShead ≥3) | −1.009 | 0.365 (0.165–0.806) | 0.013 |
AISthorax ≥3 | −0.282 | 0.755 (0.570–0.998) | 0.049 |
AISabdomen ≥3 | 0.524 | 1.689 (1.212–2.355) | 0.002 |
AISextremities ≥3 | 0.346 | 1.414 (1.078–1.854) | 0.012 |
Intubation prehospital | 1.043 | 2.837 (2.022–3.981) | <0.001 |
Chest tube prehospital | 0.506 | 1.658 (1.093–2.516) | 0.017 |
Penetrating injury | 0.369 | 1.446 (0.970–2.157) | 0.070 |
Prehospital i.v. fluids ≥1000 ml | 0.147 | 1.159 (0.980–1.370) | 0.085 |
Initial systolic blood pressure | |||
> 110 mmHg | Reference | 0.193 | |
81–110 mmHg | −1.164 | 0.312 (0.074–1.321) | 0.114 |
1–80 mmHg | 0.244 | 1.276 (0.843–1.930) | 0.249 |
0 mmHg | 0.141 | 1.152 (0.849–1.563) | 0.364 |
Age ≥60 years | −0.397 | 0.672 (0.477–0.947) | 0.023 |
Prehospital GCS score ≤8 | −0.166 | 0.847 (0.630–1.140) | 0.275 |
Constant* | −3.791 | 0.023 | <0.001 |