Fig. 1
Temporal pattern of plasma albumin (P-Albumin) (a), fractional plasma dilution calculated from changes in blood hemoglobin and hematocrit (b), and cumulative perioperative albumin shift (c), in patients (n = 10) undergoing major abdominal surgery. Bold line represents the mean value. Shaded area represents time of surgery. Changes over time were assessed by analysis of variance (p < 0.0001 for a and c, and p = 0.0006 for b) followed by Dunnett’s multiple comparison test to compare all time points to baseline. *p < 0.05, **p < 0.01, ***p < 0.001. B-Hct blood hematocrit