Table 1 Clinical and demographic characteristics of included patients
Characteristica | All patients | Patients with 4.5 g PIP/TAZ three times daily | Patients with 4.5 g PIP/TAZ two times daily |
|---|---|---|---|
(n = 60) | (n = 45) | (n = 15) | |
Female/male (n/n) | 17/43 | 13/32 | 4/11 |
Age (years) | 63 (54–75) | 63 (55–74) | 64 (54–78) |
BMI (kg/m2) | 27 (24–29) | 26 (23–29) | 29 (26–31) |
Severity scores | |||
APACHE II score | 24 (18–31) | 24 (17–32) | 24 (18–29) |
SOFA score | 11 (9–14) | 11 (9–13) | 12 (11–17) |
Laboratory values | |||
CrCl (mL/min) | 60 (24–119) | 70 (40–130) | 11 (6–19) |
Organ transplantation (n) | |||
Lung | 7 | 6 | 1 |
Liver | 8 | 4 | 4 |
Special treatments (n) | |||
RRT patients | 10 | 7 | 3 |
ECLA | 3 | 3 | 0 |
Site of infection (n) | |||
Pneumonia | 36 | 27 | 9 |
Peritonitis | 7 | 4 | 3 |
Catheter associated | 5 | 4 | 1 |
Others | 12 | 10 | 2 |
Presence of ARDS (n) | 12 | 11 | 1 |