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Table 4 Amiodarone therapy summary

From: Variable use of amiodarone is associated with a greater risk of recurrence of atrial fibrillation in the critically ill

Parameter

No AF recurrence

(n = 86)

AF recurrence

(n = 91)

Total

(n = 177)

P

Amiodarone boluses

   

0.07

 0

43 (42)

19 (25)

62 (35)

 1

51 (50)

47 (61)

98 (55)

 2

5 (5)

7 (9)

12 (7)

 3

2 (2)

3 (4)

5 (3)

Amiodarone dosing

   

<0.001

 Bolus only

3 (3)

20 (23)

23 (13)

 Infusion only

43 (43)

19 (25)

62 (35)

 Bolus and infusion

40 (47)

52 (57)

92 (52)

Delay to infusion after bolus (hours)

2 (1–3)

(n = 29)

2 (1–6)

(n = 45)

2 (1–4)

(n = 74)

0.48

Total dose amiodarone (mg)

702

(300–1117)

1366

(752–2711)

905

(488–1651)

<0.001

Infusion time (hours)

20 (12–28)

31 (20–58)

24 (16–40)

<0.001

Continuing to receive inotropes with amiodarone ceased

0 (0)

(n = 2)

23 (66)

(n = 35)

37 (100)

(n = 37)

0.14

  1. Values are shown as median (IQR) or number (%) as appropriate
  2. AF Atrial fibrillation