Algorithm-guided goal-directed haemodynamic therapy does not improve renal function after major abdominal surgery compared to good standard clinical care: a prospective randomised trial

Table 2 Fluids and catecholamines administered. Comparison between intervention groups

		Control	GDT	Mean diff. (95 % CI)	p value
Fluids
RA (ml)	OP	2316 ± 1800	2529 ± 2169	202 (−210 to 614)	0.34
RA (ml)	ICU	8052 ± 3277	8597 ± 3147	557 (−386 to 1499)	0.25
HES (ml)	OP	847 ± 1045	801 ± 1080	−50 (−237 to 138)	0.60
HES (ml)	ICU	701 ± 1188	514 ± 1083	−199 (−489 to 88)	0.17
Catecholamines
Noradrenaline (μg/kg/min)	OP	0.03 ± 0.03	0.03 ± 0.06	0.00 (−0.02 to 0.01)	0.71
Noradrenaline (μg/kg/min)	ICU	0.01 ± 0.04	0.03 ± 0.08	0.02 (−0.01 to 0.03)	0.14
Dobutamine (μg/kg/min)	OP	0.00 ± 0.03	0.74 ± 2.61	0.73 (0.18 to 1.29)	0.01
Dobutamine (μg/kg/min)	ICU	0.13 ± 0.96	0.39 ± 1.56	0.26 (−0.13 to 0.64)	0.19

Variables are given as mean ± standard deviation
GDT goal-directed haemodynamic therapy, diff. difference, CI confidence interval, RA Ringer’s acetate, HES hydroxyethyl starch, OP operation, ICU intensive care unit (the first 72 hours)

ISSN: 1364-8535