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Table 3 Diagnostic accuracy of termination of resuscitation rules for 1-month neurological outcomes

From: Applying the termination of resuscitation rules to out-of-hospital cardiac arrests of both cardiac and non-cardiac etiologies: a prospective cohort study

Etiology of cardiac arrest Neurologically unfavorable outcome Neurologically favorable outcome Sensitivity (95 % CI) Specificity (95 % CI) FPR (95 % CI) PPV (95 % CI) NPV (95 % CI)
BLS TOR rule
All types
  Met criteria 4186 7 0.808 0.971 2.9 % 0.998 0.193
  Did not meet criteria 993 238 (0.797–0.819) (0.942–0.988) (1.2–5.8 %) (0.997–0.999) (0.172–0.217)
Cardiac etiology
  Met criteria 2057 3 0.785 0.985 1.5 % 0.999 0.257
  Did not meet criteria 563 195 (0.769–0.801) (0.956–0.997) (0.3–4.4 %) (0.996–1.000) (0.226–0.290)
Noncardiac etiology
  Met criteria 2129 4 0.832 0.915 8.5 % 0.998 0.091
  Did not meet criteria 430 43 (0.817–0.846) (0.796–0.976) (2.4–20.4 %) (0.995–0.999) (0.067–0.121)
ALS TOR rule
All types
  Met criteria 1695 6 0.353 0.939 6.1 % 0.996 0.021
  Did not meet criteria 4287 93 (0.341–0.365) (0.873–0.977) (2.3–12.7 %) (0.992–0.999) (0.017–0.026)
Cardiac etiology
  Met criteria 953 3 0.294 0.963 3.7 % 0.997 0.033
  Did not meet criteria 2286 78 (0.279–0.310) (0.896–0.992) (0.8–10.4 %) (0.991–0.999) (0.026–0.041)
Noncardiac etiology
  Met criteria 742 3 0.271 0.833 16.7 % 0.996 0.007
  Did not meet criteria 2001 15 (0.254–0.288) (0.586–0.964) (3.6–41.4 %) (0.988–0.999) (0.004–0.012)
  1. ALS advanced life support, BLS basic life support, CI confidence interval, FPR false-positive rate, NPV negative predictive value, PPV positive predictive value, TOR termination of resuscitation