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Table 3 Diagnostic accuracy of termination of resuscitation rules for 1-month neurological outcomes

From: Applying the termination of resuscitation rules to out-of-hospital cardiac arrests of both cardiac and non-cardiac etiologies: a prospective cohort study

Etiology of cardiac arrest

Neurologically unfavorable outcome

Neurologically favorable outcome

Sensitivity (95 % CI)

Specificity (95 % CI)

FPR (95 % CI)

PPV (95 % CI)

NPV (95 % CI)

BLS TOR rule

All types

 

Met criteria

4186

7

0.808

0.971

2.9 %

0.998

0.193

 

Did not meet criteria

993

238

(0.797–0.819)

(0.942–0.988)

(1.2–5.8 %)

(0.997–0.999)

(0.172–0.217)

Cardiac etiology

 

Met criteria

2057

3

0.785

0.985

1.5 %

0.999

0.257

 

Did not meet criteria

563

195

(0.769–0.801)

(0.956–0.997)

(0.3–4.4 %)

(0.996–1.000)

(0.226–0.290)

Noncardiac etiology

 

Met criteria

2129

4

0.832

0.915

8.5 %

0.998

0.091

 

Did not meet criteria

430

43

(0.817–0.846)

(0.796–0.976)

(2.4–20.4 %)

(0.995–0.999)

(0.067–0.121)

ALS TOR rule

All types

 

Met criteria

1695

6

0.353

0.939

6.1 %

0.996

0.021

 

Did not meet criteria

4287

93

(0.341–0.365)

(0.873–0.977)

(2.3–12.7 %)

(0.992–0.999)

(0.017–0.026)

Cardiac etiology

 

Met criteria

953

3

0.294

0.963

3.7 %

0.997

0.033

 

Did not meet criteria

2286

78

(0.279–0.310)

(0.896–0.992)

(0.8–10.4 %)

(0.991–0.999)

(0.026–0.041)

Noncardiac etiology

 

Met criteria

742

3

0.271

0.833

16.7 %

0.996

0.007

 

Did not meet criteria

2001

15

(0.254–0.288)

(0.586–0.964)

(3.6–41.4 %)

(0.988–0.999)

(0.004–0.012)

  1. ALS advanced life support, BLS basic life support, CI confidence interval, FPR false-positive rate, NPV negative predictive value, PPV positive predictive value, TOR termination of resuscitation
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Critical Care

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