Table 1 Baseline characteristics of all IVT patients by critical care needs (n = 290)
From: ICAT: a simple score predicting critical care needs after thrombolysis in stroke patients
Characteristics | All patients | With critical care needs | Without critical care needs | p value |
|---|---|---|---|---|
(n = 290) | (n = 72) | (n = 218) | ||
Age, years: median (IQR) | 64 (53–78) | 68.5 (57–79.5) | 63 (51–77) | 0.038 |
Sex, male: n (%) | 146 (50.3) | 42 (58.3) | 104 (47.7) | 0.118 |
Race, black: n (%) | 137 (47.2) | 45 (62.5) | 92 (42.2) | 0.003 |
NIHSS: median (IQR) | 7 (5–12) | 9 (5–16) | 7 (5–11) | <0.001 |
BP, mm Hg: median (IQR) | ||||
SBP | 159 (142–181) | 180 (161–203) | 152 (140–174) | <0.001 |
DBP | 90 (80–100) | 100 (87–112) | 87 (79–100) | <0.001 |
IVT window <3 h: n (%) | 202 (69.7) | 48 (66.7) | 154 (70.6) | 0.525 |
Medical comorbidities: n (%) | ||||
Hypertension | 235 (81.0) | 65 (90.3) | 170 (78.0) | 0.021 |
Hyperlipidemia | 146 (50.3) | 38 (52.8) | 108 (49.5) | 0.634 |
Diabetes mellitus | 78 (26.9) | 23 (31.9) | 55 (25.2) | 0.265 |
Coronary artery disease | 69 (23.8) | 17 (23.6) | 52 (23.9) | 0.967 |
Reduced ejection fraction | 28 (9.7) | 8 (11.1) | 20 (9.2) | 0.639 |
Atrial fibrillation | 58 (20.0) | 19 (26.4) | 39 (17.9) | 0.118 |
Prior ischemic stroke/TIA | 80 (27.6) | 22 (30.6) | 58 (26.6) | 0.516 |
Smoking | 92 (31.8) | 18 (25.0) | 74 (33.9) | 0.157 |
Medications: n (%) | ||||
Antiplatelet agent | 130 (44.8) | 31 (43.1) | 99 (45.4) | 0.727 |
Anticoagulation | 17 (5.9) | 4 (5.6) | 13 (6.0) | 1.000 |
Statin | 110 (37.9) | 23 (31.9) | 87 (39.9) | 0.227 |
Glucose, mg/dl: median (IQR) | 120 (103–157) | 129 (106–166) | 117 (101–148) | 0.036 |
Creatinine, mg/dl: median (IQR) | 1.0 (0.9-1.3) | 1.1 (0.9-1.4) | 1.0 (0.8-1.3) | 0.008 |
GFR <60 ml/min: n (%) | 87 (30.0) | 23 (31.9) | 64 (29.4) | 0.678 |
Stroke locationa: n (%) | 0.204 | |||
Supratentorial | 268 (92.4) | 64 (88.9) | 204 (93.6) | |
Right-hemispheric | 119 (44.4) | 31 (48.4) | 88 (43.1) | |
Left-hemispheric | 149 (55.6) | 33 (51.6) | 116 (56.9) | |
Infratentorial | 22 (7.6) | 8 (11.1) | 14 (6.4) | |
LOS, days: median (IQR) | 4 (3–7) | 6 (5–12.5) | 4 (3–6) | <0.001 |
ICU stay, days: median (IQR) | 1 (1–2) | 2 (2–5) | 1 (1–2) | <0.001 |
Final diagnosis: n (%) | 0.074 | |||
Stroke | 247 (85.2) | 66 (91.7) | 181 (83.0) | |
Stroke mimic | 43 (14.8) | 6 (8.3) | 37 (17.0) | |
Discharge to home: n (%) | 163 (56.2) | 21 (29.2) | 142 (65.1) | <0.001 |
Mortality: n (%) | 17 (5.9) | 15 (20.8) | 2 (0.9) | <0.001 |