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Table 3 Neuronal damage index

From: Brief inhalation of nitric oxide increases resuscitation success and improves 7-day-survival after cardiac arrest in rats: a randomized controlled animal study

NDI Neocortex CA 1 CA 3/4 Basal ganglia
Control 2.25 ± 0.25 2.00 ± 0.71 2.50 ± 1.10 1.00 ± 0.00
20 pm iNO 2.00 ± 0.15 2.50 ± 0.50 1.60 ± 0.31 1.10 ± 0.10
40 ppm iNO 1.60* ± 0.25 3.20 ± 1.20 1.60 ± 0.40 1.00 ± 0.00
  1. Conventional hematoxylin/eosin and NeuN (Mouse anti-Neuronal Nuclei) staining was performed. A neuronal damage index (NDI) was semiquantitatively assessed in neocortex, hippocampal CA1 and CA 3/4 sectors. *P <0.05 for 40 ppm inhaled nitric oxide (iNO) vs. control mean ± standard error of the mean. Data based on cerebral tissue taken from Control animals (n = 4), and animals treated with 20 ppm (n = 10), and 40 ppm (n = 5) iNO