| |
Day 1
|
Day 2
|
Day 3
|
Day 4
|
Day 5
|
Day 6
|
Day 7
|
|---|
|
Control
|
300 ± 99
|
308 ± 104
|
373 ± 85
|
390 ± 94
|
390 ± 94
|
390 ± 94
|
403 ± 82
|
|
20 pm iNO
|
393 ± 157
|
473* ± 43
|
479* ± 37
|
482* ± 23
|
485* ± 24
|
487* ± 18
|
488* ± 17
|
|
40 ppm iNO
|
376 ± 85
|
398 ± 70
|
430 ± 54
|
454 ± 40
|
471 ± 36
|
463 ± 43
|
467 ± 45
|
- Neurological deficit score on all days following cardiac arrest and cardiopulmonary resuscitation. Control animals exhibited severe neurological dysfunction. Inhaled nitric oxide (iNO)-treated animals had better neurological outcomes, with a statistically significant difference in animals treated with 20 ppm iNO on postoperative days 2–7; *p <0.05 for 20 ppm iNO vs. control; mean ± SD. Day 1: Control, n = 5; 20 ppm iNO, n = 10; 40 ppm iNO, n = 6. Days 2–7: Control, n = 4; 20 ppm iNO, n = 10; 40 ppm iNO, n = 6
