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Table 2 Neurologic deficit score

From: Brief inhalation of nitric oxide increases resuscitation success and improves 7-day-survival after cardiac arrest in rats: a randomized controlled animal study

 

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Control

300 ± 99

308 ± 104

373 ± 85

390 ± 94

390 ± 94

390 ± 94

403 ± 82

20 pm iNO

393 ± 157

473* ± 43

479* ± 37

482* ± 23

485* ± 24

487* ± 18

488* ± 17

40 ppm iNO

376 ± 85

398 ± 70

430 ± 54

454 ± 40

471 ± 36

463 ± 43

467 ± 45

  1. Neurological deficit score on all days following cardiac arrest and cardiopulmonary resuscitation. Control animals exhibited severe neurological dysfunction. Inhaled nitric oxide (iNO)-treated animals had better neurological outcomes, with a statistically significant difference in animals treated with 20 ppm iNO on postoperative days 2–7; *p <0.05 for 20 ppm iNO vs. control; mean ± SD. Day 1: Control, n = 5; 20 ppm iNO, n = 10; 40 ppm iNO, n = 6. Days 2–7: Control, n = 4; 20 ppm iNO, n = 10; 40 ppm iNO, n = 6