Table 1 Physiologic data
BL | PR 30 | PR 60 | ||
|---|---|---|---|---|
HR (bpm) | Control | 378 ± 11 | 336 ± 9 | 364 ± 20 |
20 pm iNO | 360 ± 15 | 344 ± 12 | 372 ± 15 | |
40 ppm iNO | 389 ± 9 | 383 ± 11 | 402 ± 12 | |
Hgb (g/dL) | Control | 14.5 ± 0.2 | 15.8 ± 0.4 | 16.2 ± 0.5 |
20 pm iNO | 14.6 ± 0.3 | 15.9 ± 0.2 | 15.5 ± 0.4 | |
40 ppm iNO | 14.2 ± 0.3 | 15.3 ± 0.5 | 15.2 ± 0.4 | |
CO-Hba (%) | Control | 0.4 ± 0.1 | 0.1 ± 0.1 | 0.4 ± 0.1 |
20 pm iNO | 0.5 ± 0.1 | 0.8 ± 0.3 | 0.0 ± 1.1 | |
40 ppm iNO | 0.5 ± 0.1 | 0.1 ± 0.5 | 0.4 ± 0.3 | |
Glucose (mg/dL) | Control | 139 ± 5 | 306 ± 28 | 190 ± 29 |
20 pm iNO | 129 ± 5 | 240 ± 14 | 179 ± 15 | |
40 ppm iNO | 125 ± 7 | 204 ± 16 | 141 ± 13 | |
HCO3ˉ | Control | 27.4 ± 0.3 | 14.8 ± 1.7 | 22.2 ± 0.1 |
20 pm iNO | 27.1 ± 0.4 | 19.2 ± 1.0 | 23.0 ± 0.4 | |
40 ppm iNO | 26.7 ± 0.6 | 18.7 ± 0.6 | 22.7 ± 0.1 | |
Ph | Control | 7.4 ± 0.0 | 7.2 ± 0.1 | 7.4 ± 0.0 |
20 pm iNO | 7.4 ± 0.1 | 7.3 ± 0.0 | 7.4 ± 0.0 | |
40 ppm iNO | 7.4 ± 0.1 | 7.3 ± 0.0 | 7.4 ± 0.0 | |
PaO2 (mmHg) | Control | 131 ± 8 | 301 ± 36 | 121 ± 5 |
20 pm iNO | 136 ± 9 | 253 ± 38 | 122 ± 11 | |
40 ppm iNO | 124 ± 6 | 271 ± 21 | 132 ± 10 | |
PaCO2 (mmHg) | Control | 42 ± 2 | 42 ± 3 | 41 ± 3 |
20 pm iNO | 42 ± 2 | 48 ± 3 | 40 ± 2 | |
40 ppm iNO | 41 ± 1 | 40 ± 2 | 38 ± 1 | |
Temperature (°C) | Control | 37.4 ± 0.1 | 37.2 ± 0.2 | 37.4 ± 0.1 |
20 pm iNO | 37.3 ± 0.1 | 37.4 ± 0.1 | 37.4 ± 0.1 | |
40 ppm iNO | 37.4 ± 0.0 | 37.3 ± 0.1 | 37.3 ± 0.1 |